A survey on fractional variational calculus

Main results and techniques of the fractional calculus of variations are surveyed. We consider variational problems containing Caputo derivatives and study them using both indirect and direct methods. In particular, we provide necessary optimality conditions of Euler-Lagrange type for the fundamental, higher-order, and isoperimetric problems, and compute approximated solutions based on truncated Gr\"{u}nwald--Letnikov approximations of Caputo derivatives.Comment: This is a preprint of a paper whose final and definite form is in 'Handbook of Fractional Calculus with Applications. Vol 1: Basic Theory', De Gruyter. Submitted 29-March-2018; accepted, after a revision, 13-June-201

Optimal control strategies for tuberculosis treatment: a case study in Angola

We apply optimal control theory to a tuberculosis model given by a system of ordinary differential equations. Optimal control strategies are proposed to minimize the cost of interventions. Numerical simulations are given using data from Angola.Comment: This is a preprint of a paper whose final and definite form will appear in the international journal Numerical Algebra, Control and Optimization (NACO). Paper accepted for publication 15-March-201