283,521 research outputs found

    Intellectual

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    I received my associate degree in science in 2011, but I decided in 2021 that I wanted to achieve my Bachelor’s degree. Most nights after my daughter goes to bed, I am buried in studies. I look forward to continuing my education growing my knowledge for a new career path.https://thekeep.eiu.edu/pubh_belonging_gallery/1007/thumbnail.jp

    Social

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    This a picture of me and my two best friends at a Backstreet Boys concert last summer. We all have children, and it can be hard to coordinate schedules for a night out. They have provided love and support during some of the hardest times.https://thekeep.eiu.edu/pubh_belonging_gallery/1004/thumbnail.jp

    Spartan Daily, October 5, 1938

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    Volume 27, Issue 10https://scholarworks.sjsu.edu/spartandaily/2800/thumbnail.jp

    Charmed baryon Sigmac(2800) as a ND hadronic molecule

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    The isotriplet Sigmac(2800) baryon with possible quantum numbers J(P) = 1/2(+), 1/2(-) or 3/2(+), 3/2(-) is considered as a hadronic molecule composed of a nucleon and a D meson. We determine the strong two-body decay widths Sigmac to Lambdac + pi which are shown to be consistent with current data for the J(P) = 1/2(+) and J(P) = 3/2(-) assignments.Comment: 8 pages, 2 figure

    Signalling cell cycle arrest and cell death through the MMR System

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    Loss of DNA mismatch repair (MMR) in mammalian cells, as well as having a causative role in cancer, has been linked to resistance to certain DNA damaging agents including clinically important cytotoxic chemotherapeutics. MMR-deficient cells exhibit defects in G<sub>2</sub>/M cell cycle arrest and cell killing when treated with these agents. MMR-dependent cell cycle arrest occurs, at least for low doses of alkylating agents, only after the second S-phase following DNA alkylation, suggesting that two rounds of DNA replication are required to generate a checkpoint signal. These results point to an indirect role for MMR proteins in damage signalling where aberrant processing of mismatches leads to the generation of DNA structures (single-strand gaps and/or double-strand breaks) that provoke checkpoint activation and cell killing. Significantly, recent studies have revealed that the role of MMR proteins in mismatch repair can be uncoupled from the MMR-dependent damage responses. Thus, there is a threshold of expression of MSH2 or MLH1 required for proper checkpoint and cell-death signalling, even though sub-threshold levels are sufficient for fully functional MMR repair activity. Segregation is also revealed through the identification of mutations in MLH1 or MSH2 that provide alleles functional in MMR but not in DNA damage responses and mutations in MSH6 that compromise MMR but not in apoptotic responses to DNA damaging agents. These studies suggest a direct role for MMR proteins in recognizing and signalling DNA damage responses that is independent of the MMR catalytic repair process. How MMR-dependent G<sub>2</sub> arrest may link to cell death remains elusive and we speculate that it is perhaps the resolution of the MMR-dependent G<sub>2</sub> cell cycle arrest following DNA damage that is important in terms of cell survival

    Low-lying charmed and charmed-strange baryon states

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    In this work, we systematically study the mass spectra and strong decays of 1P1P and 2S2S charmed and charmed-strange baryons in the framework of nonrelativistic constituent quark models. With the light quark cluster-heavy quark picture, the masses are simply calculated by a potential model. The strong decays are studied by the Eichten-Hill-Quigg decay formula. Masses and decay properties of the well-established 1S1S and 1P1P states can be reproduced by our method. Σc(2800)0,+,++\Sigma_c(2800)^{0,+,++} can be assigned as a Σc2(3/2)\Sigma_{c2}(3/2^-) or Σc2(5/2)\Sigma_{c2}(5/2^-) state. We prefer to interpret the signal Σc(2850)0\Sigma_c(2850)^0 as a 2S(1/2+)2S(1/2^+) state although at present we cannot thoroughly exclude the possibility that this is the same state as Σc(2800)0\Sigma_c(2800)^0. Λc(2765)+\Lambda_c(2765)^+ or Σc(2765)+\Sigma_c(2765)^+ could be explained as the Λc+(2S)\Lambda_c^+(2S) state or Σc1+(1/2)\Sigma^+_{c1}(1/2^-) state, respectively. We propose to measure the branching ratio of B(Σc(2455)π)/B(Σc(2520)π)\mathcal{B}(\Sigma_c(2455)\pi)/\mathcal{B}(\Sigma_c(2520)\pi) in future, which may disentangle the puzzle of this state. Our results support Ξc(2980)0,+\Xi_c(2980)^{0,+} as the first radial excited state of Ξc(2470)0,+\Xi_c(2470)^{0,+} with JP=1/2+J^P=1/2^+. The assignment of Ξc(2930)0\Xi_c(2930)^0 is analogous to Σc(2800)0,+,++\Sigma_c(2800)^{0,+,++}, \emph{i.e.}, a Ξc2(3/2)\Xi^\prime_{c2}(3/2^-) or Ξc2(5/2)\Xi^\prime_{c2}(5/2^-) state. In addition, we predict some typical ratios among partial decay widths, which are valuable for experimental search for these missing charmed and charmed-strange baryons.Comment: 16 pages, 3 figures, 13 tables. Accepted by Eur. Phys. J.

    Модели атмосфер углеродных гигантов с высоким содержанием углерода

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    Рассчитано 240 моделей атмосфер углеродных гигантов с высоким содержанием углерода (2800 ≤ Tэф ≤ 3400 K, 0,06 ≤ lg(C/O) ≤ 2,7).Розраховано 240 моделей атмосфер вуглецевих гiгантiв з високим вмiстом вуглецю ((2800 ≤ Tэф ≤ 3400 K, 0,06 ≤ lg(C/O) ≤ 2,7).We calculated 240 model atmospheres for carbon giants of high carbon abundances (2800 ≤ Tef ≤ 3400 K, 0.06 ≤ log(C/O) ≤ 2.7)
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