Lateralization of cerebral function in a patient with suspected aprosodia due to left middle cerebral artery infarction

Abstract

pdf《目的》左中大脳動脈の広範な梗塞により、失語症や右半側空間無視とともにaprosodiaをはじめ右半球症状を呈した症例を経験したため、症例の機能偏在性について考察する。 《方法》症例の神経心理学的症状を整理するため、標準失語症検査やBehavioural Inattention Test行動性無視検査などの各種神経心理学検査および利き手テストを実施した。 《結果》本症例の利き手テストは両手利きの判定であった。発話は感情表現を伴わず、右半球損傷で報告されるaprosodiaと類似していた。その他の右半球症状として、談話障害や表情変化の乏しさも認めた。一方で、左半球症状の失語症は病巣の大きさに比し症状が軽く、一般的には軽度が多い右半側空間無視は中等度であった。 《結論》本症例は左脳梗塞により多彩な神経心理学的症状を呈した。利き手テストは両手利きの判定であったため、一般的な右手利き者と機能偏在性が異なっていた可能性が考えられた。Objective: To present functional lateralization observed in a patient with right hemispheric symptoms, including aprosodia, aphasia, and right unilateral spatial neglect, owing to extensive infarction in the left middle cerebral artery territory. Methods: The neuropsychologic symptoms were evaluated using various tests, including the standard language test of aphasia, behavioral inattention test, and dominant hand test. Results: The patient was ambidextrous; their speech was devoid of emotional expression, similar to aprosodia reported in patients with right hemisphere injury. Other right hemispheric symptoms were discourse deficits and poor facial expression changes. Conversely, among the left hemispheric symptoms, aphasia was mild compared to the lesion size. Furthermore, right unilateral spatial neglect, which is usually mild in similar cases, was moderate in our patient. Conclusion: The patient presented with a variety of neuropsychologic symptoms owing to a left cerebral infarction. The ambidexterity of the patient might partially explain the deviation of lateralization of cerebral function from what is typically observed in a right-handed person.departmental bulletin pape

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