research article
EEF1G (Eukaryotic translation elongation factor 1 gamma)
Abstract
Eukaryotic translation elongation factor 1 gamma, alias eEF1G, is a protein that plays a main function in the elongation step of translation process but also covers numerous moonlighting roles. Considering its importance in the cell it is found frequently overexpressed in human cancer cells and thus this review wants to collect the state of the art about EEF1G, with insights on DNA, RNA, protein encoded and the diseases where it is implicated- Article
- EEF1G
- Eukaryotic translation elongation factor 1 gamma
- Translation
- Translation elongation factor
- protein synthesis
- cancer
- oncogene
- cancer marker
- Genes Section
- Cluster Analysis
- Datasets as Topic
- Humans
- Molecular Sequence Data
- Neoplasms/*classification/genetics
- *RNA, Neoplasm
- Brain Neoplasms/*genetics
- Computational Biology/methods
- Gene Expression Profiling/*methods
- Gene Regulatory Networks/genetics
- Glioblastoma/*genetics
- Humans
- Kaplan-Meier Estimate
- Proportional Hazards Models
- Transcriptome
- Bone Marrow/growth & development/*pathology
- Flow Cytometry/methods
- Gene Expression/genetics
- Gene Expression Profiling
- Humans
- Multiple Myeloma/*genetics