3,349,259 research outputs found

    Identification of signaling pathways in early mammary gland development by mouse genetics

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    The mammary gland develops as an appendage of the ectoderm. The prenatal stage of mammary development is hormone independent and is regulated by sequential and reciprocal signaling between the epithelium and the mesenchyme. A number of recent studies using human and mouse genetics, in particular targeted gene deletion and transgenic expression, have identified some of the signals that control specific steps in development. This process involves cell specification and proliferation, reciprocal tissue interactions and cell migration. Since some of these events are recapitulated during tumorigenesis, an understanding of these signaling pathways may contribute to the development of targeted therapies and novel drugs

    Cancer Report 2007

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    Welcome letter by Cancer Center Directors 2-3 Breast Cancer Report 4-5 Analysis of 2007 Activity Report 6-9 Research 10-11 Our Story of Quality 12-13 Generous Gifts Changing Lives 14-15 About Our Cover 1

    Cancer Report 2008

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    Welcome Letter by the Directors of the Cancer Center 2-3 Stories from cancer survivors 4-5 Prostate Cancer 6-7 Kidney Cancer 8 Bladder Cancer 9 Activity Report 10-11 Cancer Research 12-13 Retirees 13 Quality Cancer Care 14-15 Survivorship 16 CLIMB® Program 17 Drive Through Colon Cancer Screening saves lives 18 Generous Gifts Changing Lives 19 Innovative Care 2
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