A Convenient Preparation of 1,2,3-Tri-O-Acetyl-Beta-D-Ribofuranose by Enzymatic Regioselective 5-O-Deacetylation of the Peracetylated Ribofuranose

Abstract

The lipase from Candida rugosa (Sigma) was used to catalyze the regioselective deacetylation at the 5-position of 1,2,3, 5-tetra-O-acetyl- beta-D-ribofuranose on a preparative scale . Enzymatic deacetylation provides a convenient one-step preparation of 1,2.3-tri-O-acetyl-beta-D- ribofuranose. (C) 2004 Elsevier Ltd. All rights reserved

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Last time updated on 20/05/2019

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