The N-terminal region of CXCL11 as structural template for CXCR3 molecular recognition: synthesis, conformational analysis and binding studies

Palladino P.; Portella L.; Colonna G.; Raucci R.; Saviano G.; Napolitano M.; Scala S.; Castello G.; Costantini S.; ROSSI, FILOMENA

oai:www.iris.unina.it:11588/458910

The N-terminal region of CXCL11 as structural template for CXCR3 molecular recognition: synthesis, conformational analysis and binding studies

Authors: Palladino P.
Portella L.
Colonna G.
Raucci R.
Saviano G.
Napolitano M.
Scala S.
Castello G.
Costantini S.
FILOMENA ROSSI
Publication date: 1 January 2012
Publisher
Doi

Abstract

We have synthesized three peptides corresponding to the N-terminal region of CXCL11 but with different aromatic amino acids, analyzed their conformtions by CD, NMR and MD, simulated their complexes with CXCR3 by docking methods and validated these data by in vitro studie

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Archivio della ricerca - Università degli studi di Napoli Federico II

oai:www.iris.unina.it:11588/45...

Last time updated on 12/11/2016

This paper was published in Archivio della ricerca - Università degli studi di Napoli Federico II.

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