The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain.

Pangeni, Rajendra P; Channathodiyil, Prasanna; Huen, David S; Eagles, Lawrence W; Johal, Balraj K; Pasha, Dawar; Hadjistephanou, Natasa; Nevell, Oliver; Davies, Claire L; Adewumi, Ayobami I; Khanom, Hamida; Samra, Ikroop S; Buzatto, Vanessa C; Chandrasekaran, Preethi; Shinawi, Thoraia; Dawson, Timothy P; Ashton, Katherine; Davis, Charles; Brodbelt, Andrew R; Jenkinson, Michael D; Bièche, Ivan; Latif, Farida; Darling, John L; Warr, Tracy J; Morris, Mark R.

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oai:wlv.openrepository.com:2436/621319

The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain.

Abstract

Tumour metastasis to the brain is a common and deadly development in certain cancers; 18-30 % of breast tumours metastasise to the brain. The contribution that gene silencing through epigenetic mechanisms plays in these metastatic tumours is not well understood

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Wolverhampton Intellectual Repository and E-theses

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Last time updated on 13/06/2018

This paper was published in Wolverhampton Intellectual Repository and E-theses.

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