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oaioai:figshare.com:article/2885587

Synthesis of Enamides via Rh/C-Catalyzed Direct Hydroacylation of Ketoximes

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Publication date
26 February 2016
Publisher
Doi

    Abstract

    Enamides were efficiently prepared via a novel Rh/C-catalyzed direct hydroacylation of ketoximes. Up to 88% isolated yield of enamides were obtained with this method. Subsequent asymmetric hydrogenation of the enamides with Rh/DuanPhos complex gave the corresponding chiral amine in excellent enantioselectivities (up to 99.7% ee)

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    The Francis Crick Institute

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    Last time updated on 16/03/2018

    This paper was published in The Francis Crick Institute.

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