Iron-Catalyzed Amidation of Alkynyl Bromides: A Facile Route for the Preparation of Ynamides

Abstract

A facile route to obtain ynamides in high yields was described. The products were achieved through the iron-catalyzed C−N coupling reaction of amides with alkynyl bromides in the presence of 20 mol % of N,N′-dimethylethane-1,2-diamine (DMEDA)

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The Francis Crick Institute

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Last time updated on 16/03/2018

This paper was published in The Francis Crick Institute.

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