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Simple and Efficient Preparation of 2,5-Disubstituted Oxazoles via a Metal-Free-Catalyzed Cascade Cyclization
Abstract
A practical and simple synthesis of 2,5-disubstituted oxazoles was developed via an iodine-catalyzed tandem oxidative cyclization. A wide range of common commercial aromatic aldehydes can be used as reaction substrates, which displayed excellent functional group compatibility in this reaction- Text
- Journal contribution
- Biochemistry
- Medicine
- Developmental Biology
- Mental Health
- Computational Biology
- Chemical Sciences not elsewhere classified
- oxazole
- Efficient Preparation
- Cyclization
- reaction substrates
- cyclization
- aldehyde
- synthesis
- Disubstituted
- Cascade
- tandem
- oxidative
- Oxazole
- group compatibility
- Simple
- disubstituted
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Last time updated on 16/03/2018
This paper was published in The Francis Crick Institute.
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