textjournal article
Chiral Calcium VAPOL Phosphate Mediated Asymmetric Chlorination and Michael Reactions of 3-Substituted Oxindoles
Abstract
We disclose a novel high yielding and highly enantioselective chiral calcium VAPOL phosphate-catalyzed chlorination of 3-substituted oxindoles with N-chlorosuccinimide (NCS). The reaction conditions are also shown to be effective for the catalytic enantioselective Michael addition of 3-aryloxindoles to methyl vinyl ketone- Text
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- Biochemistry
- Microbiology
- Molecular Biology
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- Chemical Sciences not elsewhere classified
- methyl vinyl ketone
- reaction conditions
- NCS
- aryloxindole
- Michael Reactions
- Substituted
- chlorination
- oxindole
- OxindolesWe
- enantioselective Michael addition
- chiral
- Chiral Calcium VAPOL Phosphate Mediated Asymmetric Chlorination
- calcium
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Last time updated on 16/03/2018
This paper was published in The Francis Crick Institute.
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