(Thio)urea Organocatalyst Equilibrium Acidities in DMSO
Abstract
Bordwell’s method of overlapping indicators was used to determine the p<i>K</i><sub>a</sub> values of some of the most popular (thio)urea organocatalysts via UV spectrophotometric titrations. The incremental effect of CF<sub>3</sub> groups on acidic strength was also investigated. The p<i>K</i><sub>a</sub>’s are in the range of 8.5–19.6. The results may lead to a better understanding of noncovalent organocatalysis and may aid in future catalyst development- Text
- Journal contribution
- Microbiology
- Immunology
- Science Policy
- Biological Sciences not elsewhere classified
- Chemical Sciences not elsewhere classified
- Information Systems not elsewhere classified
- future catalyst development
- acidic strength
- Equilibrium
- indicator
- CF 3 groups
- method
- pKa values
- noncovalent organocatalysis
- Thio
- Organocatalyst
- understanding
- UV
- titration
- thio
- organocatalyst
- DMSOBordwell
- Aciditie
Similar works
Full text
Last time updated on 16/03/2018
This paper was published in The Francis Crick Institute.
Having an issue?
Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.