Facile Synthesis of a Library of Lyme Disease Glycolipid Antigens

Abstract

A library of one of the two Lyme disease antigens, BbGL1, has been synthesized in four steps from d-galactose using BF3-promoted glycosylation of the peracetate to introduce the cholesteryl β-glycoside and TBTU-promoted esterification to add a range of fatty acids regioselectively at O-6 of d-galactose in good yield

Similar works

Full text

thumbnail-image

The Francis Crick Institute

redirect
Last time updated on 16/03/2018

This paper was published in The Francis Crick Institute.

Having an issue?

Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.

Licence: CC BY-NC 4.0