textjournal article
Facile Synthesis of a Library of Lyme Disease Glycolipid Antigens
Abstract
A library of one of the two Lyme disease antigens, BbGL1, has been synthesized in four steps from d-galactose using BF3-promoted glycosylation of the peracetate to introduce the cholesteryl β-glycoside and TBTU-promoted esterification to add a range of fatty acids regioselectively at O-6 of d-galactose in good yield- Text
- Journal contribution
- Medicine
- Cell Biology
- Genetics
- Biotechnology
- Ecology
- Marine Biology
- Chemical Sciences not elsewhere classified
- Information Systems not elsewhere classified
- BF
- cholesteryl
- Lyme Disease Glycolipid AntigensA library
- glycosylation
- BbGL
- glycoside
- Facile Synthesis
- esterification
- Lyme disease antigens
- peracetate
- acids regioselectively