Atroposelective Heck Macrocyclization: Enantioselective Synthesis of Bis(bibenzylic) Natural Products
Abstract
The Heck protocol was applied for the first time to the atroposelective synthesis of macrocyclic natural products. As ring closure to bis(bibenzyls) of the isoplagiochin type leads to a configurationally stable biaryl axis in the molecule, cyclization could be conducted atroposelectively in the presence of a chiral BINAP ligand- Text
- Journal contribution
- Biophysics
- Biochemistry
- Medicine
- Cell Biology
- Biotechnology
- Computational Biology
- Chemical Sciences not elsewhere classified
- Physical Sciences not elsewhere classified
- presence
- macrocyclic
- ProductsThe
- atroposelectively
- biaryl axis
- ring closure
- Bis
- configurationally
- Natural
- isoplagiochin type
- molecule
- chiral BINAP ligand
- atroposelective synthesis
- Atroposelective Heck Macrocyclization
- Enantioselective Synthesis
Similar works
This paper was published in FigShare.
Having an issue?
Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.