Receptor That Can Capture a Discrete Monohydrated Fluoride Anion

Abstract

A ‘picket calix[4]pyrrole’ bearing a well-defined binding domain has allowed the stabilization of a monohydrated fluoride anion. The monohydrated F^– was observed only when CsF (not the TBAF) was treated with a host in aqueous acetonitrile. The structure of the receptor-bound, monohydrated F^– was fully characterized by single crystal X-ray diffraction analysis as well as by low temperature ¹H and ¹⁹F NMR spectroscopy. Further analysis revealed that the complex formed a three-dimensional, salt mediated organic framework in the solid state