Abstract

Efficient Alder-ene reactions of various arynes generated directly from bis-1,3-diynes are described. The reactivity of ene donors with different tethers was examined under thermal and metal-catalyzed conditions, which indicates that both the formation of aryne intermediates and their ene reactions are less sensitive to the catalyst than to the structural features of the substrates

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The Francis Crick Institute

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Last time updated on 12/02/2018

This paper was published in The Francis Crick Institute.

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