High Efficiency Synthesis of F‑18 Fluoromethyl Ethers: An Attractive Alternative for C‑11 Methyl Groups in Positron Emission Tomography Radiopharmaceuticals
Abstract
A rapid and efficient method for the synthesis of <i>O</i>-fluoromethyl aliphatic and aromatic ethers is presented. This method is so mild that it can be used for the preparation of positron emission tomography (PET) radiopharmaceuticals bearing <i>O</i>-[<sup>18</sup>F]fluoromethyl groups- Text
- Journal contribution
- Biophysics
- Biochemistry
- Medicine
- Cell Biology
- Pharmacology
- Biotechnology
- Chemical Sciences not elsewhere classified
- Physical Sciences not elsewhere classified
- aliphatic
- Attractive
- ether
- Methyl
- High Efficiency Synthesis
- method
- synthesis
- preparation
- positron emission tomography
- Fluoromethyl
- radiopharmaceutical
- Positron Emission Tomography RadiopharmaceuticalsA
- Ether