Lewis Acid Mediated Trifluoromethylthio Lactonization/Lactamization
Abstract
A highly selective Lewis acid mediated trifluoromethylthio lactonization/lactamization of olefins is described. The reaction was proposed to proceed via a thiiranium ion intermediate, which was further attacked by the carboxylic acid or amide to generate the corresponding trifluoromethylthiolated lactone/lactam- Text
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- Trifluoromethylthio
- Mediated
- carboxylic acid
- olefins
- trifluoromethylthio
- trifluoromethylthiolated
- lactone
- thiiranium ion
- Lewis acid
- Lactonization
- amide
- lactonization