Skip to main content
Article thumbnail
Location of Repository

Click, Substitute and Fluoresce: Synthesis and Applications of 2,6-Di-(1,2,3-triazolyl)-purine Nucleosides

By Irina Novosjolova, Armands Kovaļovs, Inga Bižāne, Ērika Bizdēna and Māris Turks

Abstract

A novel class of ditriazolylpurine nucleosides were ob-tained from 2,6-diazido precursors via copper catalyzed azide-alkyne cycloaddition. These intermediates ap-peared to be very reactive towards N- and S-nucleophiles and thus selectively gave C(6)-substituted analogs with triazolyl moiety at C(2)-position. The latter products exhibit interesting fluorescence properties

Topics: ditriazolylpurine nucleosides, 1, 3-dipolar cycloaddition reaction, fluorescence
Publisher: IS3NA
OAI identifier: oai:ortus.rtu.lv:13632
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles


To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.