ウリ科植物における植物病原微生物に対する病害抵抗性機構の研究

京都大学新制・課程博士博士(農学)甲第26053号農博第2663号京都大学大学院農学研究科応用生物科学専攻(主査)教授 髙野 義孝, 教授 寺内 良平, 教授 吉田 健太郎学位規則第4条第1項該当Doctor of Agricultural ScienceKyoto UniversityDGA

哺乳類細胞の低容量ストレス応答におけるヒストンシャペロンHIRAの機能解析

京都大学新制・論文博士博士(生命科学)乙第13691号論生博第32号京都大学大学院生命科学研究科統合生命科学専攻(主査)教授 青木 一洋, 教授 河内 孝之, 教授 松本 智裕学位規則第4条第2項該当Doctor of Philosophy in Life SciencesKyoto UniversityDGA

Two Cases of Obstructive Pyelonephritis with Hyperammonemia Causing Impaired Consciousness

We herein report two cases of obstructive pyelonephritis with hyperammonemia causing impaired consciousness. One patient was a 79-year-old female. She was admitted for impaired consciousness and hematuria. Computed tomography (CT) revealed left hydronephrosis and hydroureter indicating obstructive pyelonephritis and her ammonia in the blood was a high level of 208 μg/dl. Her consciousness did not change immediately but improved 10 days after ureteral catheterization. The other patient was an 88-year-old female. She was also admitted for impaired consciousness and hematuria. CT revealed right hydronephrosis and an ureteral stone causing obstructive pyelonephritis and her ammonia level in the blood was a high level of 133 μg/dl. Her consciousness did not change immediately but improved 7 days after ureteral catheterization. Hyperammonemia in patients with obstructive pyelonephritis is a rare entity that can be occasionally observed. In patients with prolonged impaired consciousness due to urinary tract infections, clinicians should consider the possibility of hyperammonemia

散逸力学系に対するアンサンブル平方根フィルターの誤差解析

京都大学新制・課程博士博士(理学)甲第25778号理博第5089号京都大学大学院理学研究科数学・数理解析専攻(主査)教授 坂上 貴之, 教授 COLLINS Benoit Vincent Pierre, 教授 國府 寛司学位規則第4条第1項該当Doctor of ScienceKyoto UniversityDFA

春秋時期的“勇”及與“禮”“義”之關係

宇佐美文理教授退職記念論

Effects of Technical and Vocational Education and Training on Income and Employment: The Case of Students and Workers in Nairobi, Kenya

京都大学新制・課程博士博士(地域研究)甲第26124号地博第343号京都大学大学院アジア・アフリカ地域研究研究科アフリカ地域研究専攻(主査)教授 高橋 基樹, 教授 平野(野元) 美佐, 教授 高田 明, 准教授 町北 朋洋学位規則第4条第1項該当Doctor of Area StudiesKyoto UniversityDGA

Movie- and mobile-therapy without therapist involvment for patients with obsessive–compulsive disorder: Protocol for a randomized controlled trial

Background: Self-help programs without therapist involvement for obsessive–compulsive disorder (OCD) are promising, but the high dropout rate is a significant issue. Our software, which incorporates entertainment elements, showed a completion rate of over 80% in a pre–post comparison study, with superior effectiveness. This is the protocol for a study that aims to evaluate the efficacy and tolerability of a video-based mobile application for OCD treatment through a randomized controlled trial. Methods: This study is designed as a randomized controlled trial with two parallel group comparison, with assessors blinded to group allocation. The study will include outpatients aged 18 years or older diagnosed with OCD. The intervention group will receive a mobile-device-based intervention using an application grounded in cognitive behavioral therapy. The treatment period will be 8 weeks, during which 21 sessions will be conducted. Participants not allocated to the intervention group will be assigned to a waitlist control group for 8 weeks. The primary outcome for effectiveness will be the comparison of the Yale–Brown Obsessive Compulsive Scale. As the primary outcome for tolerability, participants in the intervention group who complete 80% or more of the sessions by the 8-week point will be defined as treatment completers, and the proportion of completers will be calculated. Assuming a 10% attrition rate, a total of 88 participants will be needed. Results: Results will be presented according to the protocol. Conclusions: If this study demonstrates that OCD can be improved through mobile-based self-help treatment without therapist involvement, it will become an important treatment option for patients

Changing Sources and Use of Water in Rural Mozambique: A Case Study on a Village with Introduced Handpumps in Niassa Province

京都大学新制・課程博士博士(地域研究)甲第26122号地博第341号京都大学大学院アジア・アフリカ地域研究研究科アフリカ地域研究専攻(主査)教授 高橋 基樹, 教授 伊谷 樹一, 教授 大山 修一, 准教授 原田 英典学位規則第4条第1項該当Doctor of Area StudiesKyoto UniversityDGA

Impact of Shared Child Health Record on Vaccination Completeness: A Case Study in Lao PDR

Purpose: We developed the Shared Child Health Record (SCHR) using the Fast Health Interoperability Resources International Patient Summary (FHIR IPS) standards to facilitate data interoperability between the Lao Electronic Health Record-Bahmni (EHR-Bahmni) and Electronic Immunization Record‐District Health Information Software Version 2 (EIR-DHIS2). This study evaluated the impact of vaccination completeness and coverage on the value of the SCHR. Method: We analyzed the data of Borlikhamxai Province between May 2023 and April 2024. The Stata software was used to assess and match patients across the two systems, and descriptive statistics were employed to examine demographics, compare vaccination completeness, and assess type-specific vaccine coverage across the sources. Results: 11,422 EIR-DHIS2 and 2,500 EHR-Bahmni events were transferred to the SCHR (FHIR server). After deduplication, 13,813 children were used for analysis. We discovered that the SCHR has the potential to clarify the number of vaccinated children and increase the overall coverage by 0.40–1.60%. However, in Pakxan District, where provincial hospitals primarily use EHRs, integrating EHR and EIR data into the SCHR increased vaccination coverage by 2–9% compared to EIR estimates. In addition, we found that the EIR had a higher vaccination completeness rate than the SCHR at provincial and district levels, with differences of 6.22% and 21.82%, respectively, indicating a lack of comprehensive vaccination overview with the EIR compared to the SCHR. Conclusion: Our findings suggest that the SCHR can clarify vaccination coverage and provide a more complete picture of vaccination completeness. However, the challenges encountered during the data collection process included data identification and matching, inconsistent standards, technical skill alignment, and disrupted internet connections. Nonetheless, the SCHR program potentially represents an effective method to achieve national interoperability in Lao PDR