UV-Spectrophotometric Method for Citicoline: Development and Validation

A UV-spectrophotometric technique that is simple, sensitive, specific, rigid, precise, and repeatable was created and verified for the measurement of citicoline in tablet dosage form as well as in its pure form. The highest absorbance of citicoline in 0.1N HCl was observed at 280 nm. Between 10 and 80 μg/mL, the method showed linearity with a linear regression equation of Abs = 0.0111 x Conc and a correlation coefficient of 0.9999. The method's average accuracy was 98.41 ± 0.70%, and its precision was good (%RSD ~2%). It was shown that common excipients did not significantly interfere

Predictive Implications of Dynamic Factors on Investors Decision in Indian Derivatives Market: An Empirical Study

Since the Indian derivative market is growing rapidly and participation in retail increases, the study investigates factors that affect investment decisions of retail investors. Despite market growth, investor behaviours is understood, especially in emerging economies. This study examines risk tolerance, financial literacy, market dynamics, regulatory environment and how technology/access affects investment decisions to fill this difference. The study uses a quantitative explanation-induced design, with a structured questionnaire distributed to 129 retail investors. We used convenience sampling and online recruitment to increase demographic diversity. Data analysis used descriptive and subordinate figures such as Piercen's correlation and several linear regressions to determine variable conditions. The results suggest that technology/access (β = 0.250, p = 0.002) and economic literacy (β = 0.207, p = 0.014) are the leading prophecies for investment decisions. Regulatory Environment (β = 0.184, p = 0.028) and risk tolerance (β = 0.161, p = 0.049) Make considerable impact.. The model has a strong fit, explaining 76.2% of investment decision variance (Adj. R² = 0.752, F = 77.917, p < 0.001). Conclusions emphasize the requirement for integrated guidelines to improve financial literacy, technical access, and regulatory framework. The results point to integrated policies needed to improve regulatory systems, tech access, and financial education. The findings highlight the need of comprehensive policies meant to improve regulatory systems, technology accessibility, and financial literacy

Assessing the Cytotoxic Effects of Calcium Hydroxide and Triple Antibiotic Paste on SCAP: A Systematic Review

Aim: This systematic review paper focuses on the effects of two common intracanal medicaments used in regenerative endodontic procedures on the survival of human apical papilla cells.Background: Periapical lesions form due to an inflammatory response triggered by microorganisms and their by-products invading the root canal system. Endodontic therapy aims to eliminate these microbes and disinfect the root canal system. Reducing the microbial load is crucial before obturation, as it helps alleviate symptoms and reduces the incidence of persistent periapical pathosis. This study aims to evaluate and compare the effects of calcium hydroxide and triple antibiotic paste (TAP) intracanal medicaments on the survival of human apical papilla cells.Materials & Methods: An electronic search of the Medline database (via PubMed) and Web of Science was conducted using terms such as calcium hydroxide, TAP, and intracanal medicaments. The search criteria followed the PRISMA statement guidelines. For each selected study, data were extracted: Study design and methodology, Sample size and characteristics, and Type and concentration of intracanal medicament used.Results: Twenty articles met the established criteria and were included

Ensuring Safety in Dental Clinics: A Systematic Review of Infection Control Measures

Infection control in dental clinics is a critical aspect of ensuring patient and staff safety, particularly given the high risk of cross-contamination in these settings. This systematic review examines the effectiveness of various infection control measures implemented in dental clinics, including personal protective equipment (PPE), sterilization protocols, environmental cleaning practices, hand hygiene, and aerosol management. A comprehensive search of peer-reviewed studies published between 2016 and 2025 was conducted, adhering to PRISMA guidelines. The findings highlight best practices and emerging technologies that enhance safety and compliance with global standards. Challenges such as cost, staff training, and adherence to protocols are also discussed, providing actionable recommendations for dental practitioners and policymakers. This review underscores the importance of robust infection control strategies in promoting safer dental environments and mitigating risks associated with infectious diseases

Ritual Plants of Maharashtra: Documentation, Analysis, and Cultural Significance

Festivals are integral to human culture, celebrating significant life events and spiritual occasions. Traditional festivals reflect cultural identity, fostering community and spirituality. Plants play a crucial role in these celebrations worldwide, symbolizing cultural heritage and the human-nature relationship. In India, their significance extends beyond practical use, yet research on their cultural importance remains limited.This study documents and statistically analyzes plant usage in 19 Indian festivals across different seasons. Food-related plants are central to many celebrations, with Haritalika showing the highest plant usage. Arecaceae and Poaceae are the most commonly used families, with key plants including nagli, coconut, mangoes, and nuts. Word cloud analysis highlights prominent plant-related festivals such as Gopalkala, Pola, Mangalagaur, and Diwali.A Chi-square test revealed a highly significant association between festivals and seasons (X² = 820, df = 72, p < 2.2e-16), confirmed by Cramér’s V (1) and the contingency coefficient (0.894). Flower and tree usage showed strong associations with Marathi and English months (Φ = 0.512 and Φ = 0.410, respectively). Flower (Φ = 0.412) and powder (Φ = 0.417) usage were significantly linked to festivals, highlighting their importance in religious and celebratory practices. Sentiment analysis assigned scores to plant-related phrases, indicating mild positivity for "food, worshipping" (0.4596) and neutrality for "prasad" and "decoration" (0.0000). Network analysis revealed distinct clusters of festivals and seasons, emphasizing shared cultural and temporal connections. Correspondence analysis biplots showed strong seasonal associations, with Gregorian calendar months exhibiting clearer temporal fixation than the Hindu lunar calendar.This study enhances understanding of the cultural significance of plants in festivals, reinforcing their role in biodiversity conservation and cultural heritage preservation

Studies on the Application of Leaf Isolates of Lactic Acid Bacteria as PGPR

The rhizosphere of a plant contains microorganisms that can be called plant growth-promoting rhizobacteria (PGPR), which play a crucial role in promoting plant growth and development. The beneficial effects of these bacteria on plant growth can be direct or indirect. The benefits provided by these bacteria can include increased nutrient availability, phytohormone production, and protection against several phytopathogens. PGPR has become an important strategy in sustainable agriculture due to the possibility of reducing synthetic fertilizers and pesticides, promoting plant growth, and enhancing soil quality. Lactic Acid Bacteria (LAB) are ubiquitous, Gram-positive, catalase-negative, and facultative aerophilic microorganisms. They are commonly found in a wide range of environments including food-rich environments, decaying plants, milk products, the human gut, vaginal flora, and on the skin of various living organisms. Their applications are seen in food fermentation, food preservation, the pharmaceutical industry, and dietary supplements. In addition, their presence in the rhizosphere expands their application as PGPR. The LAB isolated from soil and plant parts shows significant production of phytohormones like indole acetic acid, gibberellic acid, etc. They also show antimicrobial activity against phytopathogens. Their ability to fix nitrogen, iron chelation, phosphate solubilization, and ammonia production makes them the PGPR. In this paper, the PGPR characteristics of LAB and other reported PGPR are compared

A REVIEW ON OBESITY PREDICTION USING MACHINE LEARNING TECHNIQUES

At present, protecting the community is crucial for addressing health issues, which can be done through medical research. Obesity has emerged as a global health crisis, posing a significant risk to the future. It ranks as one of the most prevalent health issues worldwide. Timely identification of a disease can assist both healthcare professionals and patients in taking action to reduce, if not completely eliminate, the underlying cause or in preventing the symptoms of the disease from worsening. Reviewing a patient's medical history is a common approach to diagnosing a disease; however, this process can be quite time-consuming when done manually and is often susceptible to errors and high costs. Thus, there is a compulsory to scientifically create a predictive model for the development of diseases using automated methods in today's world. This research highlights the capabilities of machine learning in tackling public health issues, laying the groundwork for future studies aimed at improving obesity prediction and prevention methods. Four machine learning algorithms were engaged: Random Forest, Decision Tree, K-Nearest Neighbor, and Support Vector Machine. The results have been encouraging, with the Random Forest classifier got the highest accuracy at 96.93% among all

AI for Predictive Health Monitoring: Applications in ICU Patient Outcome Prediction

Healthcare has achieved substantial advancement through Artificial Intelligence integration because it enables better patient outcome evaluation and forecasting along with constant monitoring. Predictive health monitoring significantly enhances operations in Intensive Care Units (ICUs) by using AI-based models to examine large quantities of patient information for critical event prediction purposes along with intervention optimization. The document examines ICU patient outcome prediction through AI applications together with vital information about machine learning (ML) and deep learning (DL) methods and data entry and ethical aspects along with potential future developments

BIODIVERSITY OF BUTTERFLY SPECIES OF ORDER (LEPIDOPTERA) AND IMPACT OF CLIMATE CHANGE ACROSS DIFFERENT RURAL AREA OF GHOT, NEAR CHAMORSHI DISTRICT-GADCHIROLI (M.S.) INDIA

All of the environmental conditions played a significant role in determining the butterfly diversity and density.They serve as excellent markers of changes in the atmosphere, climate, and seasonal ecology. Being a cold-blooded invertebrate’s butterflies are easily shows significant impact by climatic changes. Present investigation carried out for one year during October 2022 to September 2023 at rural area of Ghot, near Chamorshi District-Gadchiroli (M.S.). India. In present investigation, total 21 species were recorded and identified among these include in three families Nymphalidae belongs 14 species followed by Papilionidae with 05 species and least appearance of Pierdae with 02 species. Most of the butterfly species were very commonly called as Brush-footed butterflies followed by Papilionidae commonly called as Swallowtails species and Pierdae commonly called as white and Yellows species. As per the literature its indicate that all butterflies’species has its significant importance in balancing biodiversity, so in view of the study required future planning, climate impact and host plants conservation and also focus on the current status of biodiversity of butterflies in Ghot area near Chamorshi District-Gadchiroli (M.S.) India

THE SOCIAL NECESSITY OF LANGUAGE CONTACT AND THE STUDY OF SCIENCE (For example, Uzbek and Kazakh languages)

In world linguistics, attention has increased to the issue of language contact. As is known, the development features of historically connected languages and dialects and the increase in population migrations in the world are opening a wide path to language contact. This problem has occurred at all stages of human society, but its scientific study was associated with the emergence of comparative-historical linguistics in the world in the 19th century. The “wave theory”1 that emerged during this period proved the naturalness of the contact between languages. Language contact has been called differently in world linguistics. Among them, the concept of “language union” is popular, which continued in subsequent periods. Although the concept of “language contact” does not completely replace the concept of “language union”, it can combine their common features. This raises an urgent issue for every linguistics, including Turkology, which is the basis of our research work.In world linguistics, several types of language contact are noted: language contact, bilingualism, word acquisition, interference, substrate, etc. Taking them into account in this work, it is relevant to study the issue of the reflection of the features inherent in the Uzbek language in the Kazakh literary literature created in the conditions of bilingualism in the area of these peoples as a result of a new process, namely, the contact of the languages of the Uzbek and Kazakh peoples, who historically lived in the same space1. Also, theoretical research is being developed in the science of texts that are the result of research on language contact in terms of lexical-semantic, syntactic-semantic, functional-stylistic, communicative-pragmatic and other aspects. Now, along with the theoretical study of the features of language contact, there are also works devoted to its new direction, which we are promoting, namely, the influence of the leading language in the dialectal zone on the language in contact and their use in the work of writers who have grown up in this area1, but the issue of the use of the Uzbek language and its dialect-specific features in the works of writers who have grown up in the Republic of Uzbekistan and were formed in the spirit of Uzbek dialects has not been the object of research so far. This problem is the current issue of our research work