Norovirus gastroenteritis associated with food served by housewives at home in Bihar, India: A Case-control study

DOI: 10.5281/zenodo.13118792 A retrospective case-control study was undertaken between the 17th and 24th of 2022, with participants including patients (housewives) admitted to the hospital. All the patients in hospital are from local region and are housewives. The main sources of this Norovirus infection are from the unhygienic kitchen. Unhygienic utensils in the kitchen, inadequate food storage and improper waste disposal were identified. Investigation showed that womens in kitchen used tap water for cooking but used untreated ground water to wash food ingredients and utensils. Questionnaires were returned from 35 attendees, out of total 46 questionnaires distributed (response rate 76 %).Thirty-Five cases (including 15 confirmed cases) and 45 controls were identified and interviewed (Control cases are of same age and sex of confirmed cases). All cases were aged 10–30 years old, are 35 females. We have randomly selected the 45 participants for control group. 15 of the 35 stool specimens were positive for GII Norovirus. Other stool samples tested were negative for bacterial pathogens. To detect the Norovirus, Real-time Reverse Transcription Polymerase Chain Reaction testing was conducted. By prioritizing and consistently implementing robust hand washing and utensil washing protocols, food service establishments can significantly reduce the risk of Norovirus transmission in the kitchen environment. This, combined with other sanitation and hygiene measures, can contribute to a comprehensive strategy for preventing Norovirus outbreaks and ensuring food safety. An improved vaccine development and implementation of interventions is the need for the eradication of Norovirus

Family support and self-care in the management of diabetes patients’ perspectives from Pettah region of Indian state of Kerala

DOI: 10.5281/zenodo.14012713 Patients with type 2 diabetes were recruited using convenience sampling. Inclusion criteria included being above the age of 30, having Type 2 Diabetes and being willing to be interviewed/recorded on hospital wards. Patients with other forms of diabetes, pregnancy, and cognitive impairments such as dementia, as well as inability to speak Marathi, Hindi, or English, were excluded. Twenty eligible patients (18.01%) accepted to participate. Men made up 70% of the research participants, women 30%; 60% of the participants were between the ages of 41 and 50; 85% of the participants were married; and 50% of the participants had finished lower secondary and secondary school (grades 11 and 12). Of the patients, the majority (55%) lived in joint family. The involvement of family in daily life routines significantly enhances the management of chronic conditions. As a result, self-care behaviors such as dietary management, exercise, medication are eventually developed. Participants responded positively about their family support. Older persons were happy and grateful to receive the family support.  Most of the Female participants were unhappy with the support from husband and other family members

Assessment of the Knowledge and Perception of Sex Education among School Adolescents studying in Marathwada region, Maharashtra, India: A Cross-Sectional Study

DOI: 10.5281/zenodo.11299715 Implementing sex education in schools can provide several benefits to teens. Implementing sex education in schools empowers youngsters to make informed decisions in their lives. Research indicates that sex education reduces teen pregnancy rates, provides accurate information, and decreases HIV, AIDS, and STD infections among teenagers. Therefore, sex education promotes healthy teen sexuality. A cross sectional analysis was carried out to study students' perspectives on sexuality education in secondary schools. The analysis was conducted from December to March, 2023 among school-going adolescent adolescents in class 9-12th class in two private English-medium schools located in Urban area, but the participants are lived in urban as well as rural areas. opinion of participants and their parents about the receiving the sex education in school education. At the age of 15 the participants highly opted the Don’t know 50 (12.5%), at age 16 higher opted were Yes (%), at the age 17 higher opted were Yes 104(26%) and at the age 18 higher option were Yes 105(26.25). The gender variable Males 240opted Yes 60% and females opted Yes 147 (36.75). Parents of participants Males were opted yes 390 (97.50) and 301(75.25) female opted yes. The age group 15-18 for choice for receiving sex education in school is good  296 (74), in terms of gender total 387 (96.75%) were chosen the sex education in school. As per residence total were 337 (84.25) and parents opted yes for sex education in school were 86.375%

Organ Donation awareness among farmers of selected rural area of Andhra Pradesh

DOI: 10.5281/zenodo.14525089 The study designed to analyze the knowledge and attitudes toward organ donation among farmers and laborers in Andhra Pradesh.  Health care workers play an important role in educating and raising awareness about organ donation in a community. In our research of 465 individuals, 136 were female and 329 were male.  This cross-sectional survey successfully assessed the knowledge, attitudes, and desire to donate organs. We checked Attitude and the willingness of organ donation by the question Whom would you like to donate to farmers in responded Family member 119 (39.66%) and Laborers 75 (45.45%) and the organ donation to “Any Religion”, farmers responded 50 (16.66%) and Laborers 33 (20%). As an Indian citizen with a social obligation to society to assist better people's lives, I checked this criterion using the question Should organ donation be promoted? Farmers opted YES 269 (89.66%), while laborers voted NO 132 (80%). In question: Have you ever donated blood? Farmers 190 (63.33%) chose yes, while laborers 74 (44.84%) chose no. Response to the question "Do you think it's important to bury my body "whole"? 179 (59.66%) farmers and 119 (72.12) laborers said YES. Organizing campaigns and activities to raise awareness about organ donation can assist farmers and laborers improve their knowledge and attitudes

Personalized precision medicine for personalized health care

DOI: 10.5281/zenodo.11195907 Precision medicine is a rapidly evolving field that aims to tailor medical care to individual patients based on their unique genetic, environmental, and lifestyle factors. This approach holds immense promise for revolutionizing healthcare by offering more effective treatments, preventing diseases, and improving overall health outcomes. Personalized precision medicine is an emerging field of medicine that addresses the prevention, diagnosis, and treatment of diseases by considering individuals’ genetic and genomic data, clinical data, and environment [1,2]. It represents a paradigm shift in health care and a new reality for the health care system that favors the use of more effective and safer preventive, diagnostic, and therapeutic health interventions and contributes to the sustainability of the health care system. However, the full incorporation of personalized precision medicine and its application in clinical practice raises important training challenges for health care professionals who will need to acquire competencies aimed at performing their professional practice in an optimal, efficient, and quality manner in the Spanish health care system [3,4]. Precision medicine is a fascinating area that leverages advanced technologies, including AI, to tailor healthcare to individual patients. By analyzing a patient's unique genetic profile, medical history, lifestyle, and environmental factors, precision medicine aims to provide targeted and effective treatments. In the context of cardiovascular diseases, precision medicine can help identify individuals who are more susceptible to tobacco smoke-induced platelet activation and cardiovascular events. This personalized approach can enable healthcare providers to develop targeted interventions, such as customized treatment plans, lifestyle modifications, and risk factor management, to reduce the risk of cardiovascular diseases

Assessing the Prevalence and knowledge of Cardiovascular Risk Factors among highway construction workers

DOI: 10.5281/zenodo.11408880 The aims of our study were to evaluate the prevalence and knowledge of cardiovascular risk factors in workplace and the global risk among workers. Data collected during these examinations included BMI and blood pressure as well as habits like smoking and physical exercise. The body mass index (BMI) of each worker was calculated and classified into four groups: underweight (BMI < 18.5 kg/m2), normal weight (BMI = 18.5-23.5 kg/m2), overweight (BMI 23.5-26 kg/m2), and obese (BMI > 26 kg/m2). The clinic performed the blood sample test to examine the blood glucose (fasting or random) and the total cholesterol level. Participants with hypertension were 279 (45.07%) whereas 340(54.92%) with no any hypertension. Workers with less than a 10th-grade education were more likely to be in the high-risk category, although this difference was not statistically significant. Fasting blood glucose levels were generally normal in 396 (63.97%) participants. Participants 411 (66.39%) moderate in Physical Activity. Triglyceride was generally Normal in 389 (62.22%). The majority of tobacco and alcohol users were 379 (61.22%) and 286 (46.20%), respectively. in this assessment, 596 know Alcohol consumption raises CVD risk, 503 answers NO to Exercise regularly increases CVD risk, 367 pointed Table salt use increases CVD risk, 569 are aware that obesity increases CVD risk, 602 are aware that smoking increases CVD risk, 538 are aware that hypertension increases CVD risk, and 493 Opted NO to vegetable/fruit eating increases CVD risk

AI applications in healthcare and medicine: A brief Strategy and applications

DOI: 10.5281/zenodo.11353521 Advancements in AI technology are transforming healthcare and education. This article analyzes the influence of AI in different industries and discusses its advantages in various fields, such as health care administrative, medicine, robotics for surgery, drug discovery, patient care. AI-powered predictive analytics can improve the accuracy, efficiency, and cost-effectiveness of disease diagnosis and laboratory testing. In this article, we survey the current status of AI in healthcare, as well as discuss its future. The focused question explores the impact of applying AI in healthcare settings and the potential outcomes of this application. This article highlighted the applications and importance of artificial intelligence in the healthcare sector. AI in healthcare includes medical diagnosis, patient monitoring, and administrative applications. We believe that AI will play important role in future healthcare goods. Precision medicine, powered by machine learning, is a critical improvement in healthcare. These artificial intelligence/machine learning algorithms have played critical roles in critical medical applications. Successful integration of AI in healthcare is expected to improve patient outcomes, efficiency, and access to individualized, high-quality care. AI has great potential, it is not meant to replace healthcare professionals

Seroprevalence and molecular detection of Chikungunya virus in serum of outpatients in selected area of Telangana state of India

10.5281/zenodo.10992829 CHIKV (Chikungunya virus) has already been discovered in over 110 countries in Asia, Africa, Europe, and the Americas. Transmission has been interrupted on islands where a significant part of the population gets sick and then develops immune; yet, transmission routinely continues in countries where large segments of the population have not yet been afflicted. Of the 29 sampleas, 20 were positive for antibodies against CHIKV, the 09 samples were negative. The positivity averages of IgM and IgG detected against CHIKV were 45% (27 ±29.61 (±109.67%))and 55%( 33 ±36.19 (±109.67%)) respectively. Of the total number of patients involved in this study, 12 (60%) were women and 08 (40%) were men with the mean age of 27.50 years. myalgia, Joint pain and Abdominal pain were the symptoms most reported by participants of this study. Fever, headaches, and myalgia were observed in all patients. Public health initiatives, research advancements, and community engagement are crucial in combating Chikungunya and mitigating its negative effects on the population's quality of life. Keywords: Serology, chikungunya, CHIKV, Elisa, Aedes aegypt

An Observational Analytical Study of the Fatigue Index in Young Adult with Reference to Different Mizaj

DOI: 10.5281/zenodo.12743847 Fatigue is one of the most common symptoms in clinical medicine. It is a prominent manifestation of a number of systemic, neurologic, and psychiatric syndromes, although aprecise cause will not be identified in a substantial minority of patients. Fatigue refers to the subjective human experience of physical and mental weariness, sluggishness, low energy, and exhaustion.[1] Fatigue is typically described as extreme and persistent tiredness, weakness, orexhaustion, whether mental, physical, or both. In many cases, fatigue doesn't have a clearphysical cause and can arise as a result of illness or simply from exertion, inadequate rest, or an inadequate diet. Therefore, it's best to think of fatigue as a spectrum, ranging from mild complaints that are frequently seen in the community to severe, disabling fatigue that can have significant social and economic consequences.[2] The concept of Mizaj in the Unani system of medicine is a vast area of research. Mizaj theory finds its roots in the ancient four Humors theory. This medical theory was systematized and developed by the Greek physician Buqrat (Hippocrates, 460-370 BC). He believed that the body, and diagnosis caused certain human moods, emotions, and behaviours and line of management of any disease is based upon it. In this cross-sectional descriptive study to assess the Mizaj and fatigue severity, we used Mizaj assessment proforma based on classical literature and fatigue severity scale in apparently healthy individuals of different ages and both genders & this study was carried out in students of Ayurvedic and Unani tibbia College & Hospital, Karol Bagh New Delhi

Mental Stress and Sleep quality for frontline healthcare workers exposed to the outbreak of COVID-19

10.5281/zenodo.10986925 During the early stage of the COVID-19 pandemic, anxiety symptoms were reported in 28.8% and depressive symptoms in 16.5% of the general population in China [21]. In the literature review [22-25], no difference was found between the units where the medical personnel were working during the pandemic and their anxiety levels. The current study is considered that the anxiety of medical personnel increased due to having to provide simultaneous treatment and care to both adults and children, who are very different from each other in terms of their characteristics and needs. A total of 120 health workers participated in this study. Male participants are 50(41.66%) and female participants are 70(78.33%), in which 100(83.33%) were married and 20(16.66%) were Unmarried having the work experience upto 2 years were 40(33.33%) and above 2 years experience were 80(66.66%).Among them having nursing education 62(51.66%) and medical education were 58(48.33%). The prevalence of occupational stress among CHWs was found Feel tired (43.33%) followed by emotionally exhausted (26.66%) and Feeling weak (30%) stress in the present study. Although these findings were matched on the level of stress, statistics between these two studies differ. However, no evidence of association was observed between occupational stress and other socio-demographic factors such as age, gender, education, job position, and working year. Occupational stress was significantly associated with various stressors such as under Feel tired, emotionally exhausted and Feeling weak