Response to chronic sustained hypoxia: increased cytosolic gelsolin and decreased plasma gelsolin levels

An actin binding protein, gelsolin (GSN) has two isoforms, plasma (pGSN) and cytosolic (cGSN). Changes in pGSN and/or cGSN levels have been shown to be associated with the pathogenesis of several diseases. The aim of this study was to evaluate changes in intracellular and extracellular GSNlevels with HIF-1 in animals exposed to chronic sustained hypoxia (CSH), in addition to apoptosis and the cellular redox status. The rats in the Sham group were exposed to 21% O-2, and the rats in the hypoxia groups were exposed to 13 and 10% O-2, respectively. Plasma pGSN, HIF-1 alpha, Total Antioxidant Status (TAS) and Total Oxidant Status (TOS), and lung tissue pGSN, HIF-1 alpha, TAS, TOS, GSN levels, and apoptotic cell numbers were measured. HIF-1 alpha levels were found to increase significantly in the tissue, especially in the group with severe hypoxia, both in biochemical and histological examinations. pGSN levels were also significantly decreased in both plasma and tissue. Significant increases in tissue were observed in cGSN. It was observed that while the antioxidant activity was dominant in the tissue, the oxidant activity was dominant in the plasma. In particular, the response to hypoxia regulated by HIF-1 is very important for cellular survival. The results of this study showed that the increase in cGSN and TAS levels in the lung tissue together with HIF-1 alpha can be considered as the activation of mechanisms for cellular protection.Research Fund of Nigde Omer Halisdemir University [SAT 2022/6-BAGEP]This study was supported by the Research Fund of Nigde Omer Halisdemir University (Grant No. SAT 2022/6-BAGEP)

A study on the impact of school-themed TV series on high school students and their social media usage practices

Eğitim Bilimleri Enstitüsü, Eğitim Bilimleri Ana Bilim Dalı, Eğitim Programları ve Öğretim Bilim DalıBu tez çalışmasının amacı, liseli öğrencilerin dizi izleme alışkanlıklarını incelemek, bu öğrencilerin diziler üzerinden sosyal medya kullanma pratiklerini ortaya koymak ve okul temalı dizilerin öğrenciler üzerindeki etkilerini incelemektir. Çalışmanın verileri, genel tarama modeliyle tasarlanarak Niğde il merkezinde bulunan uygun örnekleme yöntemiyle seçilen, gönüllü 479 öğrenciden toplanmıştır. Verilerin toplanması için 2 bölümden oluşan anket formu kullanılmıştır. Birinci bölümde öğrencilerin okul, sınıf ve cinsiyet bilgileri, televizyon izleme alışkanlıklarına dair sorular ile diziler üzerinden sosyal medya kullanma pratikleri ile ilgili sorular, ikinci bölümde ise okul temalı dizilerin öğrencilere etkisinin ölçüldüğü 25 maddeden oluşan likert tipi anket soruları yer almıştır. Araştırma sonuçlarına göre öğrencilerin birçoğu günlük 1-3 saat arasında televizyon izlediği ve dizileri daha çok televizyondan takip ettikleri belirlenmiştir. Dizi izlemeye başlarken oyuncular ve fragmanlar etkili olurken, dizi izlemeyi bırakmanın ana sebeplerinden biri ahlaki uygunsuz sahnelerin olduğu tespit edilmiştir. Dizileri sosyal medyada takip etmedikleri buna karşın öğrencilerin önemli bir bölümünün dizi oyuncularını sosyal medyada takip ettikleri görülmektedir. Okul temalı dizilerin öğrencilere etkisine ilişkin anketten elde edilen toplam puan cinsiyet ve sınıf seviyesine göre değişmezken, eğitim alınan liseye göre değiştiği tespit edilmiştir. Ayrıca etkinin alt boyutlarında kız öğrencilerin ve Mesleki ve Teknik Anadolu Lisesinde eğitim alan öğrencilerin tüketim ve beklenti ile iletişimdeki olumsuz deneyimler faktörlerinde diğer gruplara göre daha fazla etkilendikleri gözlemlenmiştir. Eğitimcilere ebeveynlere, araştırmacılara ve diğer paydaşlara çeşitli öneriler sunulmuştur.The aim of this thesis is to examine the TV series viewing habits of high school students, to reveal their social media usage practices through TV series and to examine the effects of school-themed TV series on students. The data of the study were collected from 479 volunteer students who were selected by convenient sampling method in Niğde city center by using a general survey model. A questionnaire form consisting of 2 sections was used to collect the data. The first part included questions about students' school, class and gender information, television viewing habits and social media usage practices through TV series, and the second part included Likert-type survey questions consisting of 25 items measuring the effect of school-themed TV series on students. According to the results of the research, it was determined that most of the students watch television between 1-3 hours a day and follow the series mostly on television. While the actors and trailers were effective in starting to watch the series, it was determined that one of the main reasons for stopping watching the series was the morally inappropriate scenes. It is seen that the students do not follow the series on social media, whereas a significant portion of the students follow the series actors on social media. While the total score obtained from the questionnaire regarding the impact of school-themed TV series on students did not change according to gender and grade level, it was determined that it changed according to the high school attended. In addition, it was observed that female students and students studying at Vocational and Technical Anatolian High School were more affected than other groups in the factors of consumption and expectation and negative experiences in communication. Various recommendations are presented to educators, parents, researchers and other stakeholders

Comparative analysis of long-term and high temperature performances of OPC based high strength mortar and silica fume based high strength geopolymer mortars

The effects of Class C fly ash (FA) contents on the performance of silica fume (SF) based high strength geopolymer mortars (HSGM) subjected to high temperatures up to 1000 degrees C are investigated. The percentages of FA substitution by SF are 10%, 15%, 20% and 25% by weight. The alkali activators used consist of sodium silicate (SS) and sodium hydroxide (SH) and are used in mixtures with SH/SS ratios of 0.3, 0.4, 0.5 and 0.6. In order to compare SF based HSGMs, ordinary Portland cement (OPC) based high strength mortar (HSM) as a control mortar is also produced with the same dosage and water content. The results at environmental temperature show that higher mechanical properties are obtained from SF based HSGMs compared to OPC based HSM. The optimum replacements of Class C FA and SH/SS ratios are 15 % and 0.3 or 0.4 in terms of mechanical properties. At 28 days, SF based HSGMs with flexural strength (ffs) of 15 MPa and compressive strength (fc) of 100 MPa can be produced without thermal curing. High reductions in the mechanical properties are seen on the OPC based HSM and SF based HSGMs subjected to high temperatures. In addition, SF based HSGMs with fc values above 25 MPa can also be obtained after exposure to 1000 degrees C. Alterations in the microstructure of OPC based HSM and SF based HSGMs under the influence of high temperatures are also examined with XRD, FTIR, SM, and FESEM/EDX analyses. Particularly, a spongy structure with volumetric expansion is seen with the formation of the glassy phase in the matrix of SF based HSGMs subjected to a temperature of 1000 degrees C.Nigde Omer Halisdemir University [MMT2023/9-BAGEP]This study is supported by Nigde Omer Halisdemir University project Effect of fly ash on the properties of alkali activated silica fume mortars, project code MMT2023/9-BAGEP

Exploring the antecedents, manifestations and coping strategies of boredom in the language classroom: A dynamic perspective

In the realm of foreign language learning, emotions play a pivotal role, yet boredom remains a largely overlooked aspect, with scant research exploring its dynamics in classroom settings. Addressing this gap, this study delves into the Turkish English as a Foreign Language (EFL) context to investigate the multifaceted nature of boredom, examining its fluctuations, antecedents, manifestations and coping strategies. Four elementary level EFL learners engaged in self-ratings, reflective journals, and focus group interviews to provide insight. The findings highlight the dynamic nature of boredom, which fluctuates within and across classes and is influenced by factors such as long lectures, language proficiency, presentations and uninteresting topics. Ultimately, boredom manifests in various formats, including students using their phones, talking to friends, dealing with other things and daydreaming. Strategies such as giving full focus, a sense of understanding, note-taking and avoiding distractions were utilised to cope with boredom. Through this exploration, this study contributes to the evolving discourse on boredom in language learning, offering tailored strategies to assist language educators in addressing this often-neglected aspect of the classroom experience

Verb in Crimean Tatar Turkish based of Nazım Keriçli's work 'Three Wishes'

Sosyal Bilimler Enstitüsü, Çağdaş Türk Lehçeleri ve Edebiyatları Ana Bilim DalıBu çalışmada Nazım KERİÇLİ'nin 'Üç İstek' adlı eseri esasında Kırım Tatar Türkçesinde fiil konusu ele alınmıştır. Kırım Tatar Türkçesi üzerine Türkiye ve Türkiye dışında yeterince araştırma yapılmamıştır. Bu çalışmamızla bu konudaki eksikliğin giderilmesine bir parça olsa da katkı sağlanmak amaçlanmıştır. Kırım Tatar Türkçesi, Türk dilinin Kuzey-Batı (Kıpçak) grubuna girer. Kırım Tatar Türkçesi Karaçay-Balkar, Kumuk, Karaim Türkçesi ile bu grubun batı kolunu oluşturur. Bugüne kadar üzerinde çalışılmayan Nazım KERİÇLİ 'nin 'Üç İstek' adlı eseri ilk defa çeviri yazıya aktarılarak Türkiye Türkçesine tercüme edilmiş ve eserde bulunan malzeme esasında Kırım Tatar Türkçesinde fiil konusu incelenmiştir. İncelememiz fiil yapım eklerini, fiilin basit ve birleşik çekimini, kişi ekleri ve çekimsiz fiil biçimleri olan fiilimsileri içine almaktadır. Türk dilinde yapım ekleri yeni kelimelerin yapımında kullanılan birimlerdir. Bir dilin gelişebilmesi, o dildeki nesne ve kavramlar için kendi bünyesinde kelimeler türetebilmesiyle mümkündür. Kırım Tatar Türkçesi, diğer Türk lehçeleri gibi sondan eklemeli bir dildir. Bu nedenle kelimelerin çekimleri ve yeni kelime türetilmesi çeşitli eklerin yardımıyla mümkün olmaktadır. Dilde mevcut köklere yine dilde mevcut eklerin getirilmesiyle yapılan türetme işi, dile büyük avantaj sağlamaktadır. Türkiye Türkçesinde olduğu gibi Kırım Tatar Türkçesinde de kök ve gövdelerin iki türü mevcuttur. Bunlar 1- fiiller 2- isimler. Bu nedenle yapım eklerinin dört çeşidi kullanılmaktadır: isimden isim yapım ekleri, isimden fiil yapım ekleri, fiilden fiil yapım ekleri ve fiilden isim yapım ekleri. Bu çalışmada ise Kırım Tatar Türkçesinde fiilden fiil yapım ekleri ve isimden fiil yapım ekleri 'Üç İstek' eseri üzerinden ele alınmıştır. Türk lehçelerinde cümlede zamanı belli etmek için fiil kip ekleri kullanılır. Diğer Türk lehçelerinde olduğu gibi Kırım Tatar Türkçesinde de cümlenin zamanını belirtmek için fiil kipleri kullanılır. Kırım Tatar Türkçesinde; şimdiki zaman, geçmiş zaman ve gelecek zaman olmak üzere üç zaman esas alınarak fiil kipleri ele alınmıştır. Türk lehçelerinde işi, hareketi ve oluşu kimin ya da neyin yaptığını ifade etmek için kişi ekleri kullanılır. Bu çalışmada da Kırım Tatar Türkçesinde kişi ekleri işlenmiştir. Eser önce Kiril harflerinden Latin harflerine transkribe edilmiş ve daha sonrada çeviri yazısı oluşturulup Türkiye Türkçesine aktarımı yapılmıştır. Çalışmanın başında Kırım Tatar Türkleri ve Kırım Tatar Türkçesi hakkında da bilgi verilmiş ve daha sonra yukarıda anlatılan çalışmalar sırasıyla ele alınmıştır. Bu çalışma ile Türklük Bilimi araştırmalarına Nazım KERİÇLİ 'nin 'Üç İstek' eseri tanıtılarak ve dil incelemesi yapılarak bir katkıda bulunmak amaçlanmaktadır. Anahtar Kelimeler: Fiiller, Fiil Çekimleri, Kırım Tatar Türkçesi, Üç İstek.In this study, the subject of verbs in Crimean Tatar Turkish will be discussed based on Nazım KERIÇLI's work called 'Three Wishes'. There has not been enough research on Crimean Tatar Turkish in Türkiye or outside Türkiye. With this study, we aim to make a small contribution to closing the gap in this regard. Crimean Tatar Turkish belongs to the Northwestern (Kipchak) group of the Turkish language. Within this group, Crimean Tatar Turkish forms the western branch, together with Karachay-Balkar, Kumyk and Karaim Turkish. Nazım KERIÇLI's work 'Three Wishes', which has not been studied until now, will be transcribed and translated into the Turkish of Türkiye for the first time, and the verb subject in Crimean Tatar Turkish will be examined on the basis of the material found in the work. Our analysis will include verb formation suffixes, simple and compound conjugation of the verb, person suffixes and verbals, which are uninflected verb forms. In the Turkish language, derivational suffixes are units used in the construction of new words. The development of a language is possible by deriving words for the objects and concepts in that language. Crimean Tatar Turkish, like other Turkish dialects, is an agglutinative language. For this reason, conjugation of words and derivation of new words are possible with the help of various suffixes. Derivation, which is done by adding certain suffixes to certain roots, provides usefulness to the language. Just as in the Turkish of Türkiye, there are two types of roots and stems in Crimean-Tatar Turkish. These are 1- verbs 2- nouns. For this reason, four types of derivational suffixes are used; noun-to-noun suffixes, noun-to-verb suffixes; verb-to-verb suffixes and verb-to-noun suffixes. This study, verb-to-verb suffixes and noun-to-verb suffixes in Crimean Tatar Turkish will be discussed through the work 'Three Wishes'. In Turkish Dialects, verb mood suffixes are used to indicate time in a sentence. Just as in other Turkish dialects, verb tenses are used to indicate the tense of the sentence in Crimean Tatar Turkish. In Crimean Tatar Turkish; verb tenses will be discussed based on three tenses: present tense, past tense and future tense. In Turkish Dialects, personal suffixes are used to express who or what does the action, movement and occurrence. In this study, personal suffixes in Crimean Tatar Turkish will be discussed. The work will first be transferred from Cyrillic letters to Latin letters, then a transcription will be created and the translation will be transferred to the Turkish of Türkiye. At the beginning of the study, information about Crimean Tatar Turks and Crimean Tatar Turkish will be given, and then the above-mentioned studies will be discussed respectively. The study is aimed to contribute to Turkology research by introducing Nazım KERIÇLI and her work and by conducting a language analysis. Key Words: Verbs, Verb Conjugations, Crimean Tatar Turkish, Three Wishes

DOĞUMLA İLGİLİ İNANIŞ VE UYGULAMALARDA “DEĞİRMEN”

Geçiş donemlerinin ilki olan doğum, aileye ve topluma yeni bir bireyin katılmasını ifade etmektedir. Doğumla beraber soyun devamlılığı sağlanmakta ve toplum hayatı içinde aileye verilen değer artmaktadır. Bu yuzden ğebeliğin sorunsuz tamamlanabilmesi için doğum oncesi donemden başlanarak doğum sonrası surece kadar halk arasında ğeliştirilen bazı uyğulama ve inanışlar ortaya çıkmıştır. Bu çalışmada; doğum oncesinde, kısırlığın/çocuksuzluğun ğiderilmesi ve istenmeyen ğebeliğin ortadan kaldırması; doğum sonrasında, kırk basması ile çocuklarda ğorulen ğelişimsel rahatsızlıklar ve son olarak doğum oncesi ve sonrası donemde sakınılması ğereken durumlarla ilğili pek çok inanış ve uyğulamada değirmen ve değirmenle ilğili unsurların tespit edilmesi amaçlanmıştır. Nitel araştırma yonteminin benimsendiği bu çalışmada dokuman incelemesine başvurulmuştur. Bu amaç doğrultusunda, Turk kulturunun onemli unsurları arasında olan değirmenin halk bilimsel açıdan onemine dikkat çekilmeye çalışılmıştır. Çalışma sonucunda değirmenlerin sadece tahılların oğutulduğu mekan olmadığı, doğum oncesi donemden başlanarak anne ve bebeğin sağlığıyla ilğili pek çok uyğulama ve inanışın icra edildiği bir uyğulama merkezi olduğu sonucuna ulaşılmıştır

Hâkânî-yi Şirvânî and Bahrü'l-Ebrârı

Sosyal Bilimler Enstitüsü, Türk Dili ve Edebiyatı Ana Bilim DalıHâkânî-yi Şîrvânî'nin Bahrü'l-Ebrâr adlı kasidesi Fars ve Türk edebiyatlarında çok derin izler bırakmış bir eserdir. Etkisi asırlara sâri böyle bir eser dünya edebiyatları içerisinde bile eşine az rastlanır bir özellik arz etmektedir. Bu çalışmada fars edebiyat tarihindeki önemi kadar Türk edebiyatı tarihinde de önemli bir yeri olan Hâkânî-yi Şîrvânî'nin Bahrü'l-Ebrâr adlı kasidesi konu olarak seçilmiştir.Kendisi de bir Türk olan Hâkânî-yi Şîrvânî'nin bu kasidesi kendisinden sonra gelen Türk şairlerini de etkilemiş ve bu bağlamda Nâsır-ı Husrev Hint sahasında, Ali Şir Nevayî Çağatay sahasında, Fuzûlî Irâk-ı Acem sahasında ve Nef'î ile Yenişehirli Avnî ise Osmanlı sahasında bu kasideye aynı dil, vezin ve kafiyede nazireler yazmışlardır. Hâkânî-yi Şîrvânî'nin Bahrü'l-Ebrâr'ının bu tarihî ve kültürel önemi bizi bu kaside üzerinde özel olarak bir tez yapma düşüncesine sevketti. Bu amaçla Hâkânî-yi Şîrvânî'den önce ve sonra bu vezin ve kafiye ile şiir yazan yüz on bir şairin matla beyitlerini tespit ederek Türkçeye tercüme ettik. Ardından Hâkânî-yi Şîrvânî'nin Bahrü'l-Ebrâr'ının önemi üzerine bir değerlendirme yaparak şiirin Farsça metnini, o metnin latin harflerine aktarılmış biçimini ve Türkçe Tercümesini yaparak kasidenin kısa bir şerhini yaptık. Ümit ediyoruz ki bu çalışma bu haliyle konuya ilgi duyan bilim insanları için yararlanacakları bir metin olacaktır. Anahtar Kelimeler: Hâkânî-yi Şîrvânî, Bahrü'l-Ebrâr, kaside, nazire, klasik Türk edebiyatı.Hâkânî-yi Şîrvânî's ode Bahrü'l-Ebrâr is a work that has left deep traces in Persian and Turkish literature. Such a work, whose influence spans centuries, is a rare feature even in world literatures. In this study, Hâkânî-yi Şîrvânî's ode called Bahrü'l-Ebrâr, which has an important place in the history of Turkish literature as well as its importance in the history of Persian literature, has been chosen as the subject. This ode of Hâkânî-yi Şîrvânî, who was also a Turk, also influenced the Turkish poets who came after him, and in this context, Nâsır-ı Hüsrev wrote verses in the same language, verse and rhyme in the Indian field, Ali Şir Nevayî in the Çağatay field, Fuzûlî in the field of Irâk-ı Acem, and Nef'î and Yenişehirli Avnî in the Ottoman field. This historical and cultural significance of Hâkânî-yi Şîrvânî's Bahrü'l-Ebrâr led us to think of making a special thesis on this ode. For this purpose, we identified the matla couplets of one hundred and eleven poets who wrote poetry with this verse and rhyme before and after Hâkânî-yi Şîrvânî and translated them into Turkish. Then, we made an evaluation on the importance of Hâkânî-yi Şîrvânî's Bahrü'l-Ebrâr and made a short commentary of the ode by making the Persian text of the poem, the Latin version of that text and the Turkish translation. We hope that this study will be a useful text for scientists who are interested in the subject. Key Words: Hâkânî-yi Şîrvânî, Bahrü'l-Ebrâr, ode, nazire, classical Turkish literature

Evaluation of Tear Stability and Ocular Surface in Patients Undergoing External Endonasal Dacryocystorhinostomy (EE-DCR) for Primary Acquired Nasolacrimal Duct Occlusion (PANDO)

The aim of our study was to show the changes in ocular surface and tear film parameters of patients who underwent external endonasal dacryocystorhinostomy (EE-DCR). For this purpose, tear film break-up time, corneal staining score, ocular surface disease index (OSDI), and Schirmer I test were performed preoperatively and postoperatively. The data obtained were compared with healthy controls. In the preoperative period, ocular surface disease index scores and corneal staining scores were higher, and Schirmer 1 and tear film break-up time were lower in group 1 compared with group 2. The ocular surface parameters were similar between the groups in the first and third postoperative months. External endonasal dacryocystorhinostomy is an important method for the restoration of deteriorated tear stability. Restoration of these disorders may be an important determinant of patient satisfaction and visual quality after surgery

Calibrating the combined hardening rule parameters for burr-free forging simulation of the torque rod joint

Joints used in the automotive industry are widely manufactured by forging. A cold upsetting process can provide burr-free forging which reduces economic loss by preventing material waste. In this study, finite element simulations for the upsetting of a torque rod joint made of 41Cr4 steel are performed. The novelty of the present study lies in the fact that the upsetting performance is investigated through simulation having hardening model in order to replace the existing forging process. The performance of hardening models is studied for an accurate simulation and optimum parameters are determined. A combination of the bilinear isotropic hardening rule and Chaboche's nonlinear kinematic hardening rule is employed with the associated flow rule and Hill48 yield criterion to set up a plasticity model of the upsetting process for the first time. The parameters of the bilinear isotropic hardening rule are determined from monotonic tensile tests. The Chaboche's parameters are determined by using hysteresis loops obtained from strain-controlled low-cycle fatigue tests. The parameters of both rules are combined. Furthermore, they are calibrated using inverse analysis based on the optimization method. Genetic algorithm is used for optimization. The experimental diameter and height measurements of the joint are compared with those obtained from the optimized model. The results show that the application of the combined hardening rule provides better prediction performance of the upset dimensions with minimum dimensional tolerance. The calibrated parameters are presented for the upsetting process. The calibrated parameters of the combined hardening model for the upsetting are YS = 446.64 MPa, TM = 3363.05 MPa, C-1 = 452.31 MPa, gamma(1) = 55.165, C-2 = 212.13 MPa, gamma(2) = 12.24, C-3 = 194.191 MPa, gamma(3) = 10.00 where YS, TM, C-1,C- gamma 1,C- C-2,C- gamma 2,C- C-3,C- gamma 3 are hardening models' parameters. Absolute percent true error (APE) is 0.19%. The parameters are YS = 1.93 MPa, TM = 6.98 MPa, C-1 = 580.79 MPa, gamma(1) = 1.08, C-2 = 597.23 MPa, gamma(2) = 0.98, C-3 = 565.05 MPa, gamma(3) = 2.87 in the case of cyclic load. APE is 1.66%. Also upsetting force requirement and material flow path are presented. The forging process can be replaced by the burr-free upsetting process with necessary changes in the die and press bench design. This replacement will save the 128-gr material per each one of the torque rod joint part.Ditas Dogan Yedek Parca Imalat ve Teknik A.S.This work was supported by Ditas Dogan Yedek Parca Imalat ve Teknik A.S. We would like to thank them for their support. We would like to thank Dr. Mehmet Seyhan, Karadeniz Technical University for providing the opportunity to use Ansys (R) software for simulations for educational purposes. We are very grateful to the reviewers for their valuable comments, which have been utilized to improve the quality of the paper

Isolation and characterization of plant-pathogenic Streptomyces species associated with potato common scab disease in Turkiye

Potato common scab (PCS), a significant potato disease, negatively impacts tuber quality. The present study was conducted to isolate and characterize pathogenic Streptomyces species associated with PCS disease in Turkiye based on their morphological, physiological and molecular characteristics. Field-grown potatoes that exhibited scab lesions were collected from four provinces in 2020-2021, and 200 bacterial isolates were obtained from netted, superficial and deep-pitted common scab lesions. Pathogenicity assays, including in vitro tuber slice and in planta radish seedling bioassays, identified 150 pathogenic isolates. Morphological and physiological characterization of 92 selected isolates revealed several Streptomyces species that exhibited diverse mycelium colours, sporulation patterns and pigmentation. Molecular analysis using 16S rRNA sequencing, species-specific primers, PCR-RFLP of the 16S-23S (ITS) region with Hpy99I restriction enzyme, and multilocus sequence analysis (MLSA) based on atpD, recA, rpoB and trpB genes revealed that S. scabiei was the dominant species, followed by S. europaeiscabiei, S. caniscabiei, S. bottropensis, S. stelliscabiei and S. turgidiscabies. PCR analysis revealed the presence of the thaxtomin synthetase genes (txtAB) in all tested samples, while the necrogenic protein (nec1) and tomatinase (tomA)-encoding genes were absent from three and two isolates, respectively. Phylogenetic analysis of 32 representative isolates conducted with sequences from 16S rRNA, species-specific PCR and MLSA confirmed their morphological identification and clustered them with reference strains. This study contributes to the understanding of distribution of Streptomyces species associated with PCS, and to our knowledge, is the first molecular confirmation of S. caniscabiei and S. turgidiscabies causing potato scab in Turkiye.Nigbreve;de OEmer Halisdemir University, Scientific Research Projects Unit [TGT 2020/19-BAGEP]; Scientific and Technological Research Council of Turkiye [121O224]The current study was part of the doctoral thesis of N.U., which was partially supported by Ni & gbreve;de OEmer Halisdemir University, Scientific Research Projects Unit (BAP project no. TGT 2020/19-BAGEP) and the Scientific and Technological Research Council of Turkiye (TUB & Idot;TAK project no. 121O224). We would like to express our gratitude to Professor Kenan Karagoez (A & gbreve;r & imath; & Idot;brahim Cecen University, Tuerkiye) and Dr Marketa Mareckova (Crop Research Institute, Czech Republic) for providing the reference Streptomyces isolates. We would also like to thank Dr Qurat ul ain Sajid for her assistance in molecular analyses