Bakker, Peter

Gooskens, Vincent

Kaaij, Rachel van der

Naafs, Ben

Wieringa, Nicolien

Woerdenbag, Herman

English

This book is a formulary describing 35 preparations covering the safe treatment of a broad range of skin diseases. The formulary focuses on effective and cheap preparations, suitable for local production and use under tropical conditions. If you want to use this book, you can either download it for free (see below), or you can order your own hard copy by sending an email to Wewi-fwn@rug.nl, mentioning your name, address, email address, occupation and intended use of the book. It will be delivered free of charge to those working as health care professionals in developing countries or regions. Others will be charged €15,- for production and shipping costs. Skin diseases are among the most common reasons for seeking medical advice in developing countries and regions. Although skin diseases are, in general, not life threatening, they may cause considerable discomfort and often have serious social implications. The potential demand for skin preparations is very high among large sections of the world’s population, which are economically disadvantaged and have little financial security. Not much scientific work has been done to determine which effective, cheap and simple dermatological preparations are suitable for the conditions that exist in tropical environments. This formulary is a step in that direction. The recommendations in the book are based on the most current scientific information available, our own investigations and practical experience. The formulary aims to help meet the basic dermatological needs in primary and secondary health care in developing countries and regions around the world. The first part of the book focuses on dermatological indications, preparations and therapy. It provides background information for the preparations considering efficacy, stability, and simplicity. The second part is a practical manual for the preparation and dispensing of the proposed dermatologicals. It also includes basic pharmaceutical methods and standards of Good Manufacturing Practice. The third part contains monographs of the preparations and raw materials. Master production forms are included in the electronic version of the book and are found on the CD that comes with the book. This book can serve many purposes. It may be used as a textbook for teaching dermatological therapy or as a manual to set up a local production unit. More specifically, it may help medical doctors, pharmacists, nurses, clinical officers and other health care workers to jointly develop local drug policies and formularies for dermatologicals, and design local production facilities. This formulary is a publication of the Beta Science Shop of the University of Groningen, the Netherlands. The book comes with a CD containing master production forms for all preparations and a pdf file of the book itself. ISBN: 978-90-367-5698-

Dissertations of the University of Groningen

Tar solution 20%	Batch quantity 1000 ml	Master manufacturing formula approved by		Prepared by:				Preparation date:				Source master manufacturing formula: Dermatological preparations for the tropics, 2nd ed.Batch number: 				Raw materials and packaging materials	Quantity prescribed	Source and batch number	Actual quantity weighed/measured 	Initials weighing	Initials controlCoal tar	200 g				Polysorbate 80	50 g				Industrial methylated spirit 95%	to 1000 ml									Glass bottle(s) with airtight closure					Preparation	In-process checks1. Mix the coal tar with the polysorbate 80.		2. Pour this mixture into approx. 800 ml industrial methylated spirit 95%. Shake this mixture occasionally during one hour. 		3. Allow to stand for 24 hours.		4. Calibrate a bottle or vessel for 1000 ml.	Calibration control	5. Decant and filter the solution into the calibrated bottle or vessel.6. Make up to volume by adding industrial methylated spirit 95% to produce 1000 ml and mix well.	Final volume:	ml2012 jfmamjjasond 2013 jfmamjjasond 2014 jfmamjjasond 2015 jfmamjjasond 2016 jfmamjjasond 2017 jfmamjjasondStorage condition  in a cool and dry place,                                   keep away from fire and heat	Yield		Shelf life                   3 months	Loss		Expiry date			Loss due to	End controls before release of batch		Checked by	Result	Batch numbers raw materials correct?			Packaging materials correct (airtight closure), in good condition and closed properly?			Labelling conform model?			Expiry date stated correctly?			Brown solution with a characteristic odour?			No particulate matter?			Are all boxes of this form filled correctly and completely?			Batch released by (name and signature)		Date:		Model of label for stock		Model of label for the patientFor external use onlyTar solution 20%Batch number and batch dateDo not use past: (production date + 3 months)Store in airtight containers in a cool and dark place.Highly flammable, keep away from fire and heat.		For external use onlyDispensing unit and dateTar solution 20% _____ mlPatient nameApply to affected parts of the skin twice daily. Do not cover with bandages. Avoid direct sunlight on the treated skin. Highly flammable, keep away from fire and heat. Do not use past (dispensing date + 2 weeks)

Dermatological preparations for the tropics. A formulary of dermatological preparations and background information on choices, production and dispensing.

https://pure.rug.nl/ws/files/14698784/mpftarsolution20.doc

Dermatological preparations for the tropics. A formulary of dermatological preparations and background information on choices, production and dispensing.

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Dissertations of the University of Groningen