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Calibration of ionic and cellular cardiac electrophysiology models
Authors
Abriel
Ahrens-Nicklas
+277 more
Al Abed
Aliev
Andrianakis
Apgar
Arevalo
Ball
Ballouz
Balser
Banga
Banyasz
Bassingthwaighte
Bauer
Beattie
Beaumont
Beaumont
Bebarova
Beeler
Behar
Bers
Bers
Bett
Bezanilla
Bishop
Bondarenko
Bot
Boyett
Brennan
Britton
Britton
Britton
Brown
Brynjarsdóttir
Bueno-Orovio
Bueno-Orovio
Cairns
Cannon
Carbonell-Pascual
Celentano
Chaloner
Chandler
Cherry
Clancy
Clancy
Clancy
Clerx
Clerx
Clerx
Cobelli
Colatsky
Colman
Colman
Colquhoun
Colquhoun
Cooper
Cooper
Cooper
Corrado
Corrado
Corrado
Courtemanche
Coveney
Csercsik
Csercsik
Daly
Davies
Decker
Degasperi
Destexhe
Devenyi
DiFrancesco
Dokos
Drovandi
Dutta
Edeson
Eichel
Eisner
Elkins
Elshrif
Epstein
Fabbri
Fabbri
Faber
Fastl
Fenton
Fink
Fink
Fink
Fink
Fragoso
Fredkin
Gadsby
Garny
Gelman
Goldberger
Golowasch
Gong
Grandi
Gray
Gray
Green
Groenendaal
Gutenkunst
Gábor
Hafner
Hansen
Hass
Hastie
Hedley
Heijman
Heijman
Herrera-Valdez
Hilgemann
Hines
Hodgkin
Hodgson
Hodgson
Holland
Horn
Horn
Hosein-Sooklal
Hund
Hunter
Hutter
Irvine
Jaeger
Jaeger
Jafri
Johnstone
Kargol
Kargol
Kaur
Keener
Kennedy
Koivumäki
Krogh-Madsen
Krogh-Madsen
Lambert
Lancaster
Lawson
Lee
Lee
Lei
Lei
Lei
Lei
Lei
Lenk
Li
Li
Li
Liepe
Linz
Loewe
Lombardo
Lombardo
Luo
Lyddon
MacLeod
Mahajan
Maleckar
Mann
Marder
Mathias
Mazhari
McAllister
Menon
Milescu
Milescu
Millonas
Millonas
Mirams
Mirams
Mirams
Mirams
Mitchell
Moreno
Muszkiewicz
Neher
Nelder
Ni
Niederer
Niederer
Noble
Noble
Noble
Noble
Nygren
O'Hara
Oliver
Owen
Paci
Paci
Paci
Pan
Passini
Passini
Pathmanathan
Pathmanathan
Pathmanathan
Pathmanathan
Perissinotti
Plumlee
Podziemski
Ponnaluri
Potse
Prakosa
Qu
Quinn
Raba
Rajamani
Ranjan
Ranjan
Rasmusson
Raue
Ravagli
Read
Redfern
Rees
Rice
Richter
Roden
Rudy
Ryan
Sadrieh
Sarkar
Saucerman
Schälte
Sher
Sherman
Shotwell
Siekmann
Sigg
Silva
Smith
Smucker
Stadtländer
Starmer
Sterratt
Syed
Teed
Terkildsen
Tomek
Tran
Tsien
Tusscher
Tusscher
Tveito
Tveito
US National Research Council
Vandenberg
Vandenberg
VanDongen
Verkerk
Vernon
Villaverde
Villaverde
Walch
Waltemath
Wang
Waterfall
Weiss
White
Whittaker
Whittaker
Whittaker
Wilhelms
Willms
Winslow
Winslow
Workman
Yang
Yu
Yue
Zaniboni
Zaydman
Zhang
Zhou
Publication date
1 January 2020
Publisher
'Wiley'
Doi
Cite
Abstract
© 2020 The Authors. WIREs Systems Biology and Medicine published by Wiley Periodicals, Inc. Cardiac electrophysiology models are among the most mature and well-studied mathematical models of biological systems. This maturity is bringing new challenges as models are being used increasingly to make quantitative rather than qualitative predictions. As such, calibrating the parameters within ion current and action potential (AP) models to experimental data sets is a crucial step in constructing a predictive model. This review highlights some of the fundamental concepts in cardiac model calibration and is intended to be readily understood by computational and mathematical modelers working in other fields of biology. We discuss the classic and latest approaches to calibration in the electrophysiology field, at both the ion channel and cellular AP scales. We end with a discussion of the many challenges that work to date has raised and the need for reproducible descriptions of the calibration process to enable models to be recalibrated to new data sets and built upon for new studies. This article is categorized under: Analytical and Computational Methods > Computational Methods Physiology > Mammalian Physiology in Health and Disease Models of Systems Properties and Processes > Cellular Models
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