A Bacterial Mutant Library as a Tool to Study the Attack of a Defensin Peptide

Abstract

Defensin attack! Here we report the screening of human defensin 5 against the Keio Collection of E. coli strains. The results of this screen further our understanding of how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.United States. National Institutes of Health (DP2OD007045