The MENISCUS study investigated menstrual health and reasons for school absenteeism among adolescent girls in Uganda. The quantitative dataset contains questionnaire responses provided by 352 female students (one record per row), aged 12-20 (median age 16 years) recruited from four secondary schools in Entebbe sub-district, Uganda, in October and November 2015.  Variables cover knowledge and perceptions about menstrual hygiene management and reasons for school absenteeism, as well as socio-demographic characteristics of each respondent. Qualitative data collected through in-depth interviews with selected girls are not included in the data collection

A El-Darahali

A Senra Varela

A Shiotani

AA Sima

Antonio Amaya-Vidal

Antonio Lorenzo-Peñuelas

Avelino Senra-Varela

BJ Marshall

CT Shun

D Palli

DA Israel

F Farinati

Germán Santamaría-Rodriguez

GR Davies

H Livett

H Suwa

H Yamagata

HH Xia

HJ Son

J McCord

J Wei

JM Nigro

JR Crowther

Juan-Bosco Lopez-Saez

JV Gannon

K Hibi

K Murakami

KH Chang

KS Shim

L Chen

LP Andersen

Margarita Dominguez-Villar

MJ Domek

MJ Sanderson

MR Straton

MS Wu

N Takahashi

N Uemura

NE Hellman

P Correa

P Lauren

PC Konturek

R Palmeiro

RA Feldman

S Danese

SE Crowe

T Hongyo

Victoria Gómez-Biondi

Wu M Li-Cheng

YH Choe

YH Shiao

Zhang

Journal of Experimental & Clinical Cancer Research

PubMed

Victoria Gomez-Biondi

German Santamaria-Rodriguez

Antonio Lorenzo-Penuelas

Springer - Publisher Connector

Concurrent overexpression of serum p53 mutation related with Helicobacter pylori infection

Background & Aims In the province of Cadiz (Spain), the adjusted mortality rate for gastric cancer in the coastal town of Barbate is 10/100.000 inhabitants, whereas in the inland town of Ubrique, the rate is twice as high. The rate of Helicobacter pylori (H. pylori) infection (H. pylori antibodies) in the normal population was 54% in Ubrique, but only 32% in Barbate. In the two decades since its original discovery, p53 has found a singularly prominent place in our understanding of human gastric cancer and H. pylori cause accumulation of reactive oxygen species in the mucosa compartment. This study was designed to compare serum levels of p53 in a population characterized by high mortality due to stomach cancer and a high prevalence of H. pylori infection and another population in which mortality from this cause and the prevalence of H. pylori infection are low. Materials and methods 319 subjects from the low mortality population and 308 from the high mortality population were studied, as were 71 patients with stomach cancer. We measured serum immunoglobulin G antibody to H. pylori and serum mutant p53 protein and ceruloplasmin. Results The difference between the two populations in the prevalence of H. pylori infection was significant (p < 0.001). Of the seropositive, 81% had elevated values of mutant p53, in comparison with 11% of the seronegative (p < 0.0001). Serum concentration of ceruloplasmin was significantly higher in seropositive with elevated mutant p53 protein than in seronegative with normal levels of p53 (p < 0.05). Conclusions There is a significant association between infection with H. pylori, elevated titers of H. pylori antibodies, and positivity for serum mutant p53 protein. Such information can significantly increase our basic knowledge in molecular pathology of gastric cancer and protection against H. pylori infection

Lopez-Saez, J-B

Gomez-Biondi, V

Santamaria-Rodriguez, G

Dominguez-Villar, M

Amaya-Vidal, A

Lorenzo-Penuelas, A

Senra-Varela, A

Spiral - Imperial College Digital Repository

Weiss, Helen

Nakinyingi-Miiro, Jessica

Sembajjwe, Wilber

LSHTM Data Compass

Data for: "Menstrual health and school absenteeism among adolescent girls in Uganda (MENISCUS):  feasibility study"

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Abstract Background & Aims In the province of Cadiz (Spain), the adjusted mortality rate for gastric cancer in the coastal town of Barbate is 10/100.000 inhabitants, whereas in the inland town of Ubrique, the rate is twice as high. The rate of Helicobacter pylori (H. pylori) infection (H. pylori antibodies) in the normal population was 54% in Ubrique, but only 32% in Barbate. In the two decades since its original discovery, p53 has found a singularly prominent place in our understanding of human gastric cancer and H. pylori cause accumulation of reactive oxygen species in the mucosa compartment. This study was designed to compare serum levels of p53 in a population characterized by high mortality due to stomach cancer and a high prevalence of H. pylori infection and another population in which mortality from this cause and the prevalence of H. pylori infection are low. Materials and methods 319 subjects from the low mortality population and 308 from the high mortality population were studied, as were 71 patients with stomach cancer. We measured serum immunoglobulin G antibody to H. pylori and serum mutant p53 protein and ceruloplasmin. Results The difference between the two populations in the prevalence of H. pylori infection was significant (p  Conclusions There is a significant association between infection with H. pylori, elevated titers of H. pylori antibodies, and positivity for serum mutant p53 protein. Such information can significantly increase our basic knowledge in molecular pathology of gastric cancer and protection against H. pylori infection.</p

Lorenzo-Peñuelas Antonio

Amaya-Vidal Antonio

Dominguez-Villar Margarita

Santamaría-Rodriguez Germán

Gómez-Biondi Victoria

Lopez-Saez Juan-Bosco

Senra-Varela Avelino

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Data for: "Menstrual health and school absenteeism among adolescent girls in Uganda (MENISCUS): feasibility study"

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