10noopenopenMarcassa, C; Giubbini, R.; Acampa, W.; Cittanti, C.; Djepaxhija, O.; Gimelli, A.; Kokomani, A.; Medolago, G.; Milan, E.; Sciagrà, R.Marcassa, C; Giubbini, Raffaele; Acampa, W.; Cittanti, C.; Djepaxhija, O.; Gimelli, A.; Kokomani, A.; Medolago, Giuseppe; Milan, E.; Sciagrà, R

Acampa, W.

Cittanti, C.

Djepaxhija, O.

Gimelli, A.

Giubbini, R.

Kokomani, A.

Marcassa, C.

Medolago, G.

Milan E.

Sciagrà R.

C. Marcassa

R. Giubbini

W. Acampa

C. Cittanti

O. Djepaxhija

A. Gimelli

A. Kokomani

G. Medolago

E. Milan

R. Sciagrà

Crossref

Journal of Nuclear Cardiology

Impact of imaging protocol on left ventricular ejection fraction using gated-SPECT myocardial perfusion imaging

Marcassa, C

Milan, E.

Sciagrà, R.

GIUBBINI, Raffaele

MEDOLAGO, Giuseppe

Archivio istituzionale della ricerca - Università di Brescia

Background. There are limited data on the impact of the imaging protocol (single-day stress-rest, SD, vs. dual-day, DD) on the change in left ventricular (LV) ejection fraction (EF) (post-stress-rest) in relation to ischemia and on outcome.Methods. Using propensity score matching procedure, 490 of 1121 patients with known CAD, undergoing a SD or a DD in a multicenter study, were evaluated. Stress and rest gated-SPECT myocardial perfusion imaging was used to quantify LV perfusion, EF, and volumes. Outcome was assessed at an average follow-up time of 3.2 years.Results. Post-stress LVEF in SD and DD were comparable across all degrees of ischemia. The change in LVEF in patients with severe ischemia was, however, higher in the DD protocol, independent of the extent of CAD. At follow-up, 240 patients (49.0%) required coronary revascularization (CR) and 52 patients (10.6%) had hard events. The ischemic burden was independently associated with CR and hard-events; the post-stress LVEF was associated with CR but the change in EF was not predictive of either CR or hard events.Conclusions. In patients with severe ischemia, underestimation of post-stress myocardial stunning could be observed with the SD protocol. Post-stress LVEF and the extent ischemia, but not the change in EF, are predictive of CR and hard events

CITTANTI, Corrado

Sciagrà R.

Archivio istituzionale della ricerca - Università di Ferrara

English

There are limited data on the impact of the imaging protocol (single-day stress-rest, SD, vs. dual-day, DD) on the change in left ventricular (LV) ejection fraction (EF) (post-stress-rest) in relation to ischemia and on outcome

Giubbini, R

ACAMPA, WANDA

Cittanti, C

Djepaxhija, O

Gimelli, A

Kokomani, A

Medolago, G

Milan, E

Archivio della ricerca - Università degli studi di Napoli Federico II

https://iris.unife.it/retrieve/handle/11392/2354696/245266/Cardio%203%20-%20J%20Nucl%20Cardiol.%202016%20Apr%206.%20%5bEpub%20ahead%20of%20print%5d.pdf

Impact of imaging protocol on left ventricular ejection fraction using gated-SPECT myocardial perfusion imaging

Abstract

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Archivio istituzionale della ricerca - Università di Brescia

Archivio istituzionale della ricerca - Università di Ferrara

Archivio istituzionale della ricerca - Università di Ferrara

Archivio della ricerca - Università degli studi di Napoli Federico II