研究了铅、锌对菲律宾蛤仔的急性毒性，以及铅、锌混合液在菲律宾蛤仔体内的积累和对过氧化氢酶酶活性的影响.结果表明：铅的毒性略大于锌的毒性（96HlC50值分别为14.28，16.40Mg/l）：铅、锌混合液对蛤仔体内的重金属吸收存在交互作用，高浓度的锌（6Mg/l）明显地抑制蛤仔对高浓度铅的吸收；铅和锌的浓度为（3Mg/l）时对蛤仔的重金属吸收均有促进作用；高浓度的铅和锌混合液对蛤仔过氧化酶活性亦有显著的交互作用.呈拮抗效应.Accumulation of mixture of lead and zinc and their toxic effect on the activities of Catalase (CAT)in clam following various exposure concentration were studied in laboratory.The 96h LC50 values of lead andzinc for clam were 14.28 mg/L.16.40mg/L, respectively.the toxicities of two kinds of metals were in sequence of Ph＞Zn.Lead and zinc bioaccumulated in the study showed that different organ has different capacities for accumulating metal.with high levels in the gill.followed by soft body.and comparative lesseramounts in the fluid of cavity.The ratio of accumulation of lead in gill and soft body was far larger than thatof zinc.The clam was strong accumulator of lead.while was weak accumulator of zinc.The L9 (34)factortests showed a significant interaction between Zn and Ph on the activities of CAT in clam.indicated the antagonistic effect of Ph and Zn of CAT activities
