Berg, Marc

Bilo, Henk J. G.

Hart, Huberta E.

Meyboom-de Jong, Betty

Redekop, William K.

English

Background &amp; objectives: An ideal instrument for the assessment of health related quality of life (HRQOL) in patients with diabetes mellitus type I (T1DM) should incorporate the benefits of both generic and disease-specific instruments. The objective of this study was to investigate the responsiveness and the ability to provide information about diabetes-specific associations with HRQOL, of two generic instruments, in comparison with two diabetes-specific instruments, in patients with T1DM.Methods: In a Dutch cohort of 234 patients with T1DM we longitudinally assessed HRQOL using both generic and diabetes-specific instruments. We investigated the responsiveness, the associations with diabetes-specific variables and the Identification of specific patients by the Instruments used.Results: The generic RAND-36 was able to detect statistically significant and clinically relevant changes in HRQOL over time. Moreover, the RAND-36 was associated with (changes In) diabetes. specific variables. The generic and diabetes-specific Instruments partly Identified different patients with lowest HRQOL.Interpretation &amp; conclusion: The RAND-36 was highly responsive to changes in HRQOL in patients with T1DM and revealed diabetes-specific associations with HRQOL. A low correlation between the generic and diabetes-specific instruments and partly different identification of patients with lower HRQOL support the complementary use of these instruments In patients with T1DM.</p

Proceedings - University of Groningen

Health related quality of life in patients with type I diabetes mellitus:generic &amp; disease-specific measurement

https://pure.rug.nl/ws/files/6706443/Hart_2007_Indian_J_Med_Res.pdf

Health related quality of life in patients with type I diabetes mellitus:generic & disease-specific measurement

Abstract

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Proceedings - University of Groningen

Health related quality of life in patients with type I diabetes mellitus:generic &amp; disease-specific measurement

Abstract

Similar works

Full text

Available Versions

Proceedings - University of Groningen

Health related quality of life in patients with type I diabetes mellitus:generic & disease-specific measurement