We study the compatibility between the BPSTSU(2) instanton and the fuzzy
four-sphere algebra. By using the projective module point of view as an
intermediate step, we are able to identify a non-commutative solution of the
matrix model equations of motion which minimally extends the SU(2) instanton
solution on the classical sphere S4. We also propose to extend the
non-trivial second Chern class with the five-dimensional noncommutative
Chern-Simons term