Matrix Product States, Projected Entangled Pair States, and variational renormalization group methods for quantum spin systems

This article reviews recent developments in the theoretical understanding and the numerical implementation of variational renormalization group methods using matrix product states and projected entangled pair states.Comment: Review from 200

ANALYTIC SINGULARITIES SUPPORTED BY A SPECIFIC INTEGRAL HOMOLOGY SPHERE LINK

The main question we target is the following: If one fixes a topological type (of a complex normal surface singularity) then what are the possible analytic types supported by it, and/or, what are the possible values of the geometric genus? We answer the question for a specific (in some sense pathological) topological type, which supports rather different analytic structures. These structures are listed together with some of their key analytic invariants

Correlation Abnormal Ankle-Brachial Index and Multivessel Coronary Artery Disease in Acute Coronary Syndrome Patients

BACKGROUND: Many studies showed the association between peripheral artery disease (PAD) and coronary artery disease (CAD). The anklebrachial index (ABI) was a simple, noninvasive, and not expensive test that showed high sensitivity and specificity in the diagnosis of PAD. Previous studies showed PAD correlation with the number of coronary artery lesions and higher complexity of the lesions. These correlations might contribute to worse cardiovascular outcomes, especially acute coronary syndrome (ACS) cases. Aim of this study is to evaluate the correlation abnormal ABI with the risk of ACS patients to have multivessel coronary artery lesions.METHODS: This was a retrospective analytical casec ontrol study. The data were taken from Dr. Wahidin Sudirohusodo Hospital medical records from November 2015 to February 2016. The inclusion criteria were (>18 years old) patients with ACS who had underwent ABI examination and coronary angiography.RESULTS: The prevalence of patients with ST-elevation myocardial infarction (STEMI) was lower than non-ST elevation ACS (NSTE-ACS). The prevalence of patients with abnormal ABI was 43.3% and patients with multivessel CAD was 65%. Male patients dominated the ACS population with 73.3%, about half of patients were smoking, and 86.7% had dyslipidemia. Patients with abnormal ABI and multivessel disease had greater number than patients with normal ABI (p=0.025). Analysis with binary logistic regression model showed abnormal ABI(odd ratio [OR] 4.83; p=0.021) and male sex (OR 19.35; p=0.010) were associated with greater risk of multivessel CAD.CONCLUSION: An abnormal ABI is associated with greater risk of multivessel CAD in ACS patients

Production Rule Verification for Quasi-Delay-Insensitive Circuits

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Selenocysteine, pyrrolysine and the unique energy metabolism of methanogenic archaea

Methanogenic archaea are a group of strictly anaerobic microorganisms characterized by their strict dependence on the process of methanogenesis for energy conservation. Among the archaea, they are also the only known group synthesizing proteins containing selenocysteine or pyrrolysine. All but one of the known archaeal pyrrolysine-containing and all but two of the confirmed archaeal selenocysteine-containing protein are involved in methanogenesis. Synthesis of these proteins proceeds through suppression of translational stop codons but otherwise the two systems are fundamentally different. This paper highlights these differences and summarizes the recent developments in selenocysteine- and pyrrolysine-related research on archaea and aims to put this knowledge into the context of their unique energy metabolism

Cooperative platform (facsnanort-qpcr): contribution to the successful management of patients with mrd leukemia

t(9;22) Ph translocation is a chromosome abnormality recurrent in human chronic myelogenous leukemia (CML) and cases of childhood acute lymphoblastic leukemia (ALL). Ph is a marker of adverse prognosis significant with remission more frequent and earlier and lower percentage of overall survival. If there are less than 5% blasts in a bone marrow sample, the patient is in "clinical remission". In the light of sensitivity current controls molecular (10-6) are an important role in therapy, although this depends on the amount of cells analyzed. Our goal is to improve the sensitivity by proposing a platforms combination, which allow MRD evaluation with only 10 cells. Flow cytometry sorting (multiparameter immunological detection), nano-PCR (RNA isolation and RT) and qPCR (diagnostic confirmation). The molecular remission has many more probability to be lasting that the cytogenetic remission, both before and after the transplant. We consider this technique as an important step forward towards performed diagnosis, monitoring treatment responses, and identification of relapse in Leukemia patients

Postoperative Pyoderma Gangrenosum in Association with Renal Cell Carcinoma and Chronic Lymphocytic Leukemia

INTRODUCTION: Pyoderma gangrenosum (PG) is a rare sterile neutrophilic dermatosis characterized by painful recurrent ulcerations. It is frequently associated with inflammatory bowel disease, rheumatoid arthritis, or malignancies. PG is a diagnosis of exclusion, and it is based on clinical presentation, histology, history of an underlying disease, and exclusion of other causes of ulceration. CASE REPORT: The authors report a 62-year-old male who developed a nonhealing ulcer at the site of incision following nephrectomy for renal cell carcinoma. Past medical history included chronic lymphocytic leukemia treated with rituximab. Histology of the skin lesion showed a phlegmonous nonspecific inflammation without being able to differentiate between a necrotizing wound infection and PG. The patient’s condition was initially diagnosed as an infectious process and treated accordingly. After unsuccessful results with systemic antibiotics, high-dose corticosteroids induced prompt healing of the wound. On these bases, the diagnosis of postoperative PG within chronic lymphocytic leukemia and renal cell carcinoma was made. CONCLUSION: Faced with postoperative necrotizing ulceration resistant to correctly administered antibiotics, PG must be considered. In such condition, the diagnosis must not be guided primarily by histology and early advice of a dermatologist is recommended