Materials with Built-in Logic

Nanostructured signal-responsive materials were coupled with a combination of enzyme-based biocatalytic chemical reactions to yield information-processing responsive hybrid materials with built-in Boolean logic. The combination of enzymatic reactions performed AND/OR logic operations, transducing biochemical input signals into macroscopic structural changes of the materials, thus resulting in the amplification of the biochemical signals. The information-processing hybrid materials could be scaled up to biocomputing networks composed of many logic gates mimicking biological systems and effectively processing complex biochemical information, resulting in reversible changes of macroscopic structures and allowing adaptation of materials to environment changes.Peer reviewe