Synthesis, characterisaion and antimicrobial activity of polypropylenamine metallodendrimers modified with 1,8-naphthalimides

Two novel metal complexes of modified with 1,8-naphthalimide poly(propylenamine) dendrimer of first generation have been synthesized and characterized. By different analytical methods it was shown that the complex composition includes one ligand and one metal ion. The antimicrobial activity of the dendrimer and metallodendrimers was investigated in vitro against different Gram-positive and Gram-negative bacteria and yeasts. The antibacterial effect of thin polylactide film impregnated with the new compounds was also evaluated.The authors acknowledge Grant N H09/03-2016, Fund “Scientific Research”, Ministry of Education and Science of Bulgaria. PB acknowledges Spanish Ministry of Economy and Competitively (MINECO) for financial support MAT2012-31709 IG and PB also acknowledge COST CA15114 “Anti-MIcrobial Coating Innovations to prevent infectious diseases (AMICIPeer Reviewe