2 research outputs found
Molecular Recognition of Zwitterions with Artificial Receptors
Many biomolecules exist as internal ion pairs or zwitterions within a biologically relevant pH range. Despite their importance, the molecular recognition of this type of systems is specially challenging due to their strong solvation in aqueous media, and their trend to form folded or selfâassembled structures by pairing of charges of different sign. In this Minireview, we will discuss the molecular recognition of zwitterions using nonânatural, synthetic receptors. This contribution does not intend to make a full inâdepth revision of the existing research in the field, but a personal overview with selected representative examples from the recent literature.Financial Support from the Ministry of Science, Innovation and Universities (RTI2018â096182âBâI00, MCIU/AEI/FEDER, EU), and AGAUR (2017 SGR 208) are gratefully acknowledged.Peer reviewe