The association between VO₂/DO₂ and ScvO₂. VO₂/DO₂: oxygen extraction ratio; ScvO₂: central venous oxygen saturation.

<p>The association between VO₂/DO₂ and ScvO₂. VO₂/DO₂: oxygen extraction ratio; ScvO₂: central venous oxygen saturation.</p

Correlation between oxygen balance parameters and CO₂-gap.

<p>_cvCO₂-gap and VO₂/DO₂ and ScvO₂ (on the left); _vCO₂-gap and VO₂/DO₂ and ScvO₂ (on the right). cvCO₂-gap: central venous-to-arterial carbon dioxide difference; VO₂/DO₂: oxygen extraction ratio; ScvO₂: central venous oxygen saturation; vCO₂-gap: mixed venous-to-arterial carbon dioxide difference.</p

ROC analysis for determining VO₂/DO₂>30%.

<p>_cvCO₂-gap: central venous-to-arterial carbon dioxide difference;</p><p>_vCO₂-gap: mixed venous-to-arterial carbon dioxide difference;</p><p>P_(cv-a)CO₂/C_(a-cv)O₂: the central venous-to-arterial pCO₂ difference divided by the difference of the arterio-venous oxygen content;</p><p>P_(v-a)CO₂/C_(a-v)O₂: the mixed venous-to-arterial pCO₂ difference divided by the difference of the arterio-venous oxygen content;</p><p>ScvO₂: central venous oxygen saturation; SvO₂: mixed venous oxygen saturation.</p

Hemodynamic effects of isovolemic anemia. These data have been published earlier [12].

<p>Hb- Hemoglobin, HR- Heart rate, MAP- Mean arterial pressure, CVP- Central venous pressure, CI- Cardiac index, GEDI- Global end-diastolic volume index, ELWI- extravascular lung water index, dPmx- Index of left ventricular contractility. T₀- Baseline measurement, T₁-T₅- Five intervals of bleeding.</p><p>*p<.05 compared with T₀; ^#p<.05 compared with previous; GLM repeated measures ANOVA.</p

Descriptives (Median±IQR).

<p>_cvCO₂-gap: central venous-to-arterial carbon dioxide difference; _vCO₂-gap: mixed venous-to-arterial carbon dioxide difference; P_(cv-a)CO₂/C_(a-cv)O₂: the central venous-to-arterial pCO₂ difference divided by the difference of the arterio-venous oxygen content; P_(v-a)CO₂/C_(a-v)O₂: the mixed venous-to-arterial pCO₂ difference divided by the difference of the arterio-venous oxygen content; ScvO₂: central venous oxygen saturation; SvO₂: mixed venous oxygen saturation; DO₂: oxygen delivery; VO₂: oxygen consumption; VO₂/DO₂: oxygen extraction ratio; ERO₂: simplified oxygen extraction ratio; PaCO₂: arterial partial pressure of carbon dioxide; PaO₂: arterial partial pressure of oxygen * p<.05 as compared to baseline, ^§ p<.05 significant difference between mixed venous and central venous blood with Friedman and Wilcoxon tests, ^# Data published earlier <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0105148#pone.0105148-Kocsi1" target="_blank">[12]</a>.</p

Additional file 1: of Effects of intraoperative PEEP optimization on postoperative pulmonary complications and the inflammatory response: study protocol for a randomized controlled trial

SPIRIT 2013 Checklist: recommended items to address in a clinical trial protocol and related documents. (DOCX 52 kb

Changes of cardiac index throughout the experiment.

<p>Changes of cardiac index throughout the experiment.</p

Changes of stroke volume index throughout the experiment.

<p>Changes of stroke volume index throughout the experiment.</p

Changes of mean arterial pressure throughout the experiment.

<p>Changes of mean arterial pressure throughout the experiment.</p

Hemodynamic and blood gas parameters.

<p>Hemodynamic and blood gas parameters.</p