6 research outputs found
Raw data: Leaching ratio (μg/g) of mercury from Tibetan medicine Zuotai,β-HgS and α-HgS in different pH solutions
<p><i>Zuotai</i>, a known Tibetan medicinal mixture
containing insoluble cubic mercuric sulfide (β-HgS), has been used to treat
diseases with long history. The mercury leaching ratio from <i>Zuotai </i>in gastrointestinal pH environment
is one determinant factor for its bioavailability and biological effect.
However, the information is still scarce now. Therefore, the study was designed
to investigate the mercury leaching from <i>Zuotai</i>,
β-HgS, and α-HgS in different pH solutions</p><p>Solutions
with different pH values (1–13) were prepared from pure water, HCl solution,
and NaOH solution; the pH was monitored using a pH meter. The solutions were as
follows: HCl solution with pH = 1, HCl solution with pH = 3, HCl solution with
pH = 5, NaOH solution with pH =
7, NaOH solution with pH = 9, NaOH solution with pH = 11, and NaOH solution
with pH = 13. A solid-liquid ratio of 1:100 was adopted in all leaching
experiments. Digestion, peristalsis and emptying of drug in the
gastrointestinal tract were simulated <i>in
vitro</i>. We detected the mercury released in solutions using Automatic Direct
Mercury Analyzer. Leaching Ratio of Mercury (μg/g)=[Total Weight of Mercury
Released (μg)]/[Total Weight of Substance Tested (g)]</p><p>The results
showed that the mercury leaching
ratios of <i>Zuotai </i>at pH 1 and pH 13 were
significantly higher than those at each point within pH 3–11; the mercury leaching ratio of <i>Zuotai</i> at pH 1 was higher than that at pH 13. The mercury leaching ratio of β-HgS slightly decreased from pH 1 to pH 3
and significantly increased from pH 3 to pH 13. The mercury leaching ratio of
β-HgS at pH 13 was far higher than that at pH 1. For α-HgS,
the mercury leaching ratio also slightly decreased from pH 1 to pH 3 and then
gradually increased from pH 3 to pH 13. The mercury leaching ratio of α-HgS at
pH 1 was lower than that at pH 13.</p><p>
</p><p>Taken
together, strong acidic or strong alkaline environments would promote the
dissociation of mercury from <i>Zuotai</i>,
β-HgS, and α-HgS.</p
Raw data: Mercury leaching ratio (μg/g) from Tibetan medicine Zuotai,β-HgS and α-HgS in pure water and artificial gastrointestinal juices containing Cys(or GSH) or not.
<p><i>Zuotai</i>, a known Tibetan
medicinal mixture containing insoluble cubic mercuric sulfide (β-HgS), has been
used to treat diseases with long history. The mercury leaching ratio from <i>Zuotai </i>in
gastrointestinal environment is one determinant factor for its bioavailability
and biological effect. However, the information is still scarce now. Therefore,
the study was designed to investigate the effect of sulfhydryl biomolecules
[L-cysteine (Cys) and glutathione (GSH)] on mercury leaching from <i>Zuotai</i>,
β-HgS, and α-HgS in artificial gastrointestinal juices or pure water.</p>
<p>The artificial gastric juice and artificial intestinal juice were prepared
according to the methods described in <i>Chinese Pharmacopoeia </i>(2010
version). The following solutions were prepared: Cys in pure water (5.21
g/L), GSH in pure water (13.21 g/L), Cys in artificial gastric juice (5.21
g/L), GSH in artificial gastric juice (13.21 g/L), Cys in artificial intestinal
juice (5.21 g/L), and GSH in artificial intestinal juice (13.21 g/L). The moles
of Cys and GSH in this study were 0.215 mmol—the same as that of β-HgS and
α-HgS. A solid-liquid ratio of 1:100 was adopted in all leaching experiments.
Digestion, peristalsis and emptying of drug in the gastrointestinal tract were
simulated <i>in vitro</i>. We detected the mercury released in solutions
using Automatic Direct Mercury Analyzer. Leaching Ratio of Mercury
(μg/g)=[Total Weight of Mercury Released (μg)]/[Total Weight of Substance
Tested (g)]</p>
<p>The results showed the following trend for
the mercury leaching ratio of<i> Zuotai</i>: artificial gastric juice >
artificial intestinal juice > pure water, whereas the trend for β-HgS and
α-HgS was as follows: artificial intestinal fluid > artificial gastric fluid
> pure water. The mercury leaching ratios of <i>Zuota</i>i, β-HgS, and
α-HgS significantly increased in artificial intestinal juice containing L-Cys
or GSH compared to that without sulfhydryl biomolecules in the juice. However,
in pure water and artificial gastric juice with Cys or GSH, the mercury
leaching ratio of <i>Zuotai </i>reduced remarkably, in contrast to
the results observed for β-HgS and α-HgS.</p><div><p></p></div
Data File 1: Wavelet phase extracting demodulation algorithm based on scale factor for optical fiber Fabry-Perot sensing
The underlying values of Figure 2 Originally published in Optics Express on 26 December 2016 (oe-24-26-29506
Data File 2: Wavelet phase extracting demodulation algorithm based on scale factor for optical fiber Fabry-Perot sensing
The underlying values of Figure 3 Originally published in Optics Express on 26 December 2016 (oe-24-26-29506
Fast and Enhanced Broadband Photoresponse of a ZnO Nanowire Array/Reduced Graphene Oxide Film Hybrid Photodetector from the Visible to the Near-Infrared Range
In
the present work, a ZnO nanowire array/reduced graphene oxide
film hybrid nanostructure was realized, and the photovoltaic responses
from the visible to the near-infrared range were investigated. Compared
with the pure ZnO nanowire array and rGO thin film, the hybrid composite
exhibited a fast and greatly enhanced broadband photovoltaic response
that resulted from the formation of interfacial Schottky junctions
between ZnO and rGO
Rationally Designed Graphene/Bilayer Silver/Cu Hybrid Structure with Improved Sensitivity and Stability for Highly Efficient SERS Sensing
A simple and cost-effective strategy
was rationally designed to
fabricate a special sandwich structure consisting of graphene, bilayer
silver, and a copper plate, which was used as a surface-enhanced Raman
scattering (SERS) substrate for highly efficient SERS sensing and
detection of trace molecules. Silver dendrite (AgD) nanostructures
were subsequently grown on a silver nanosphere (AgNS)/Cu surface to
form a bilayer silver/Cu structure, which showed a 1.5-fold Raman
enhancement compared to that of the AgNS/Cu substrate. After depositing
graphene on the bilayer silver/Cu substrate to obtain a sandwich structure,
a higher SERS enhancement and better durability were enabled. The
SERS performances, measured by a portable Raman instrument, showed
that the optimized sandwich structure substrate exhibited high SERS
sensitivity to crystal violet (CV) and rhodamine 6G (R6G) with low
limit of detection of 10<sup>–9</sup> and 10<sup>–8</sup> M, respectively. Such a sandwich-structured substrate exhibited
good reproducibility across the entire detection areas with an average
relative standard deviation less than 5.9%, which permits its reliable
quantitative detection of CV and R6G molecules. In addition, graphene
both effectively improved the SERS performances and protected Ag nanocrystals
from oxidation, which endowed the sandwich structure a long-term stability
with deviation of characteristic peaks’ intensity lower than
3.6% after 25 days. This study indicates that the graphene/bilayer
silver/Cu sandwich structure as a SERS substrate has a great potential
in detecting environmental pollutants