The effect of animal husbandry on economic growth: Evidence from 13 provinces of North China

Promoting animal husbandry industry is important to help strengthen the agricultural sector. This study starts from both socio-economic and natural factors perspectives. Based on an exploratory spatial analysis, spatial econometric model, and geographically weighted regression (GWR) model, selecting the 13 Provinces of North China as the study area, this study analyzes the spatio-temporal differences and the driving factors. This study found: 1) Between 2006 and 2017, the spatial and temporal differences of GDP in the 13 provinces were statistically significant, with increased total production values and a slowed growth of the industry. In addition, the study area showed an east-west dichotomy in husbandry industry. 2) GDP had shown obvious spatial agglomeration, of which areas with the high production value were in east of Beijing, and areas with low production value were in western Inner Mongolia, Xinjiang and Gansu. 3) Population, animal husbandry output values, numbers of large livestock, and cultivated areas had greatly influenced the GDP of 13 provinces in north China. 4) The three influencing factors on GDP in the 13 provinces were found to be population, animal husbandry output values, and the sizes of cultivated areas. We should synthesize these influencing factors, supplemented with public policy concessions and compensatory measures to develop policies for improving the level of local economic development. Based on this, this study aims to provide a reference for decision making to promote the coordinated development of livestock husbandry and economic growth in China, and even provide a scientific reference for the management of similar pastoral areas in the world

Transcriptome analysis of germ cell changes in male Chinese mitten crabs (Eriocheir sinensis) induced by rhizocephalan parasite, Polyascus gregaria

The parasitism by Polyascus gregaria on Eriocheir sinensis induces feminization of the appearance of male crabs, misleading fishermen to bring them to the breeding ponds as female crabs to cultivate broodstock selection. However, there are few studies on whether P. gregaria feminizes the male germ cells, resulting in a decline in the fecundity of male crabs. Therefore, this study aims to clarify the changes in gene expression levels of male crab testes after being parasitized by P. gregaria through transcriptome sequencing to evaluate the change in fecundity. We selected parasitized and healthy male crabs from a pond culture for comparison of gene expression in germ cells. The results showed that, compared with healthy male crabs, there were 104 genes with significantly different expressions, of which 79 were up-regulated and 25 were down-regulated. These genes are mainly focused on the cytoskeleton pathway in cell components and cellular protein complex assembly in biological processes. Several spermatogenesis-related genes, such as Kazal-type protease inhibitor, which inhibits gelatinolytic activities of sperm proteases, and juvenile hormone esterase 6, which degrades methyl farnesoate, were up-regulated; while the down-regulated expression of certain heat shock proteins may lead to spermatogenic dysfunction. In addition, some immune-related genes, such as double whey acidic protein domain-containing protein and serine proteinase inhibitor 3, were significantly up-regulated. These results indicated that P. gregaria changed the development process and cell structure of male host germ cells to inhibit sperm proliferation and maturation, while multiple immune pathways in the hosts were activated to resist P. gregaria invasion

JARVIS-1: Open-World Multi-task Agents with Memory-Augmented Multimodal Language Models

Achieving human-like planning and control with multimodal observations in an open world is a key milestone for more functional generalist agents. Existing approaches can handle certain long-horizon tasks in an open world. However, they still struggle when the number of open-world tasks could potentially be infinite and lack the capability to progressively enhance task completion as game time progresses. We introduce JARVIS-1, an open-world agent that can perceive multimodal input (visual observations and human instructions), generate sophisticated plans, and perform embodied control, all within the popular yet challenging open-world Minecraft universe. Specifically, we develop JARVIS-1 on top of pre-trained multimodal language models, which map visual observations and textual instructions to plans. The plans will be ultimately dispatched to the goal-conditioned controllers. We outfit JARVIS-1 with a multimodal memory, which facilitates planning using both pre-trained knowledge and its actual game survival experiences. JARVIS-1 is the existing most general agent in Minecraft, capable of completing over 200 different tasks using control and observation space similar to humans. These tasks range from short-horizon tasks, e.g., "chopping trees" to long-horizon tasks, e.g., "obtaining a diamond pickaxe". JARVIS-1 performs exceptionally well in short-horizon tasks, achieving nearly perfect performance. In the classic long-term task of $\texttt{ObtainDiamondPickaxe}$, JARVIS-1 surpasses the reliability of current state-of-the-art agents by 5 times and can successfully complete longer-horizon and more challenging tasks. The project page is available at https://craftjarvis.org/JARVIS-1Comment: update project pag

Construction and optimization of ecological security pattern based on landscape ecological risk assessment in the affected area of the Lower Yellow River

In the context of urban expansion and climate change, the world is under pressure from multiple ecological risks. Key ecological protection areas play a pivotal role in preserving ecological stability and promoting development. Due to its unique geographical conditions, the Yellow River basin has been facing huge ecological risk pressure. In the affected area of the Lower Yellow River (AALYR) as an agricultural hub, ecological protection has gradually become a key factor restricting the development of cities and agriculture. Taking AALYR as an example, the landscape ecological risk assessment (LERA) system is established based on three aspects “natural environment—human society—landscape pattern”. We construct a comprehensive cumulative resistance surface based on the risk assessment results as the basis for the future study. Ecological corridors are identified by minimum cumulative resistance (MCR) models to establish and optimize Ecological security pattern (ESP) in the AALYR. We found that the landscape ecological risks (LER) in the study area show a uniform spatial distribution, with a slightly higher distribution in the northeast than the southwest. The ecological risk levels are generally high in AALYR, indicating a more severe risk problem in this area. A total of 56 ecological sources were identified, with a total area of 21176 km2. The ecological sensitivity of AALYR was high, and 99 ecological corridors and 59 ecological nodes were extracted. Ecological corridors and nodes were consistently and densely distributed throughout the study area. The network analysis method improves the stability of the network structure after optimization. Based on the key components of the ESP, with the combination of geographical characteristics and local policy planning guidance, we constructed the “One Belt and One Axis, Two Cores and Two Corridors, Four zones” ESP. The study results may offer guidance and suggestions for the construction of ESP and ecological environment protection system in the world’s major river basins, and may also provide information for ecological planning of other similar river basins in the world

Life-Expectancy Disparities Among Adults With HIV in the United States and Canada: The Impact of a Reduction in Drug- and Alcohol-Related Deaths Using the Lives Saved Simulation Model.

Improvements in life expectancy among people living with human immunodeficiency virus (PLWH) receiving antiretroviral treatment in the United States and Canada might differ among key populations. Given the difference in substance use among key populations and the current opioid epidemic, drug- and alcohol-related deaths might be contributing to the disparities in life expectancy. We sought to estimate life expectancy at age 20 years in key populations (and their comparison groups) in 3 time periods (2004-2007, 2008-2011, and 2012-2015) and the potential increase in expected life expectancy with a simulated 20% reduction in drug- and alcohol-related deaths using the novel Lives Saved Simulation model. Among 92,289 PLWH, life expectancy increased in all key populations and comparison groups from 2004-2007 to 2012-2015. Disparities in survival of approximately a decade persisted among black versus white men who have sex with men and people with (vs. without) a history of injection drug use. A 20% reduction in drug- and alcohol-related mortality would have the greatest life-expectancy benefit for black men who have sex with men, white women, and people with a history of injection drug use. Our findings suggest that preventing drug- and alcohol-related deaths among PLWH could narrow disparities in life expectancy among some key populations, but other causes of death must be addressed to further narrow the disparities

Missing Data on the Estimation of the Prevalence of Accumulated Human Immunodeficiency Virus Drug Resistance in Patients Treated With Antiretroviral Drugs in North America

Determination of the prevalence of accumulated antiretroviral drug resistance among persons infected with human immunodeficiency virus (HIV) is complicated by the lack of routine measurement in clinical care. By using data from 8 clinic-based cohorts from the North American AIDS Cohort Collaboration on Research and Design, drug-resistance mutations from those with genotype tests were determined and scored using the Genotypic Resistance Interpretation Algorithm developed at Stanford University. For each year from 2000 through 2005, the prevalence was calculated using data from the tested subset, assumptions that incorporated clinical knowledge, and multiple imputation methods to yield a complete data set. A total of 9,289 patients contributed data to the analysis; 3,959 had at least 1 viral load above 1,000 copies/mL, of whom 2,962 (75%) had undergone at least 1 genotype test. Using these methods, the authors estimated that the prevalence of accumulated resistance to 2 or more antiretroviral drug classes had increased from 14% in 2000 to 17% in 2005 (P < 0.001). In contrast, the prevalence of resistance in the tested subset declined from 57% to 36% for 2 or more classes. The authors’ use of clinical knowledge and multiple imputation methods revealed trends in HIV drug resistance among patients in care that were markedly different from those observed using only data from patients who had undergone genotype tests

Risk Factors for Tuberculosis After Highly Active Antiretroviral Therapy Initiation in the United States and Canada: Implications for Tuberculosis Screening

Background. Screening for tuberculosis prior to highly active antiretroviral therapy (HAART) initiation is not routinely performed in low-incidence settings. Identifying factors associated with developing tuberculosis after HAART initiation could focus screening efforts

Late Presentation for HIV Care in the United States and Canada

Initiatives to improve early detection and access to HIV services have increased over time. We assessed the immune status of patients at initial presentation for HIV care from 1997-2007 in 13 US and Canadian clinical cohorts

End-Stage Renal Disease Among HIV-Infected Adults in North America

Background. Human immunodeficiency virus (HIV)-infected adults, particularly those of black race, are at high-risk for end-stage renal disease (ESRD), but contributing factors are evolving. We hypothesized that improvements in HIV treatment have led to declines in risk of ESRD, particularly among HIV-infected blacks

Research on Palletizing Robot System of Multi - axis Synchronous Control Technology

Due to the increasing demand for personalized objects, the palletizing packaging of personalized objects has attracted people’s attention. To improve the efficiency of the palletizing system, a palletizing robot based on multi-axis synchronous control technology is proposed in this paper. The robot takes SIMATIC S7 - 1200 PLC as the control core, uses the master command synchronization method to achieve multi-axis synchronization control, and realizes human-computer interaction through PROFINET communication with the touch screen. The multi-sensor is connected with the input and output modules of the PLC, and the review of the grasping object is realized. After the robot is put into use, the flexibility of the palletizing system is improved, the multi-axis synchronous control technology is improved, and the palletizing efficiency of personalized objects is greatly increased