Fluctuations of the Josephson current and electron-electron interactions in superconducting weak links

We derive a microscopic effective action for superconducting contacts with arbitrary transmission distribution of conducting channels. Provided fluctuations of the Josephson phase remain sufficiently small our formalism allows to fully describe fluctuation and interaction effects in such systems. As compared to the well studied tunneling limit our analysis yields a number of qualitatively new features which occur due to the presence of subgap Andreev bound states in the system. We investigate the equilibrium supercurrent noise and evaluate the electron-electron interaction correction to the Josephson current across superconducting contacts. At T=0 this correction is found to vanish for fully transparent contacts indicating the absence of Coulomb effects in this limit.Comment: 12 pages, 4 figure

Triplet superconductivity in a ferromagnetic vortex

We argue that odd-frequency triplet superconductivity can be conveniently realized in hybrid superconductor-ferromagnet (SF) structures with a ferromagnetic vortex. We demonstrate that due to proximity-induced long-range triplet pairing such SFS junctions can sustain appreciable supercurrent which can be directly measured in experiments.Comment: 4 pages, 3 figure

Towards quantitative prediction of proteasomal digestion patterns of proteins

We discuss the problem of proteasomal degradation of proteins. Though proteasomes are important for all aspects of the cellular metabolism, some details of the physical mechanism of the process remain unknown. We introduce a stochastic model of the proteasomal degradation of proteins, which accounts for the protein translocation and the topology of the positioning of cleavage centers of a proteasome from first principles. For this model we develop the mathematical description based on a master-equation and techniques for reconstruction of the cleavage specificity inherent to proteins and the proteasomal translocation rates, which are a property of the proteasome specie, from mass spectroscopy data on digestion patterns. With these properties determined, one can quantitatively predict digestion patterns for new experimental set-ups. Additionally we design an experimental set-up for a synthetic polypeptide with a periodic sequence of amino acids, which enables especially reliable determination of translocation rates.Comment: 14 pages, 4 figures, submitted to J. Stat. Mech. (Special issue for proceedings of 5th Intl. Conf. on Unsolved Problems on Noise and Fluctuations in Physics, Biology & High Technology, Lyon (France), June 2-6, 2008