Sonocatalyzed facile synthesis of 2-aryl benzoxazoles using MnO₂ nanoparticles as oxidant agent under mild conditions

<p>Nano MnO₂ was found to be an efficient oxidant agent for the synthesis of 2-substituted benzoxazoles through one-pot reaction of <i>o</i>-aminophenol and different aromatic aldehydes in acetonitrile under ultrasonic irradiation. This method was performed under mild conditions with high yields, inexpensive and readily available oxidant agent, facile and easy experimental procedure, simple purification of final products, and short reaction times. The prepared nano MnO₂ has been characterized by FTIR, XRD, and SEM techniques. The pure products were identified and characterized by physical and spectroscopic data such as; melting point, IR, ¹H NMR, and ¹³C NMR.</p