Uji Sensitivitas Mycobacterium Tuberculosis Terhadap Obat Anti Tuberkulosis Pada Penderita Tuberkulosis Paru Dengan Diabetes Melitus

Diabetes mellitus is a chronic disease marked with high blood sugar levels. Patients with diabetes mellitus susceptible to pulmonary tuberculosismaking it difficult for to cure them. This research aims to find out figure of anti tuberculosis drug resistance in patients with pulmonary tuberculosis with diabetes mellitus. This descriptive research was conducted in the Laboratory of Microbiology Center for Lung Disease Treatment Lubuk Alung West Sumatra. Sputum samples were pulmonary tuberculosis patients with diabetes mellitus as many as 10 samples. The results of Mycobacterium tuberculosis sensitivity to anti-tuberculosis drugs in patients with pulmonary tuberculosis with diabetes mellitus showed resistance to one drug, isoniazid by 10% and the other anti tuberculosis drugs are not resistance

Pengaruh Latihan Submaksimal Terhadap Kadar Interleukin-6 Pada Siswa Pusat Pendidikan Latihan Pelajar Sumatera Barat

This study to determine the effect of submaximal exercise on muscle tissue and endothelial damage in athletes indicated by increased levels of IL-6 plasma in the students of The Education Center and Sport Training Student West Sumatera. This study was experimental pre and post-test group design to 17 students sport of football in PPLP West Sumatera. IL-6 before and after exercise submaximal examined was method by ELISA. Statical analysis was bypaired samples t-test and the results obtained statistically significant when p <0,05. The results showed the mean levels IL-6 before the submaximal exercise 4,2±2,8 pg/ml and 7,2±3,6 pg/ml after exercise. The increase levels of IL-6 statistically highly significant p<0,001

Kualitas Sperma Ejakulat Pejantan Ayam Kukuak Balenggek Pada Pengandangan Tunggal Terisolasi (Ejaculated Sperm Quality of Isolated Single Caging of Balenggek Chickens)

The Balenggek chicken is a long crower type fowl. This fowl have isolated and caging in single cage for years to result the long crower sound.This study was carried out to identify the influence of fed to the ejaculate sperm quality of balenggek chickens. First, the sperm were collected from isolated caging of Balenggek fowl more or less than three years and un-isolated caging of Balenggek fowl as control group. Second, the sperm were collected from isolated caging of Balenggek fowl more or less than three years and un-isolated caging of Balenggek fowl as control group, after treated by 124 ComFed for three months. The sperm were collected by massages methods and analyze with counting chamber of Improve Neubauer. Slides of sperm were stained by Eosin. Variables observed were sperm ejaculated, colours, and sperm consistency. The results shows that the sperm quality of Balenggek fowl increased (from 2.5 billion sperm/ml to 3.5 billion sperm/ml) significantly higher (p&lt;0.05) in isolated caging fowl with reschedule feeding. Sperm color and its consistency were increased from + (c quality) to ++ (b quality). It can conclude that single caging could decreased the ejaculated sperm of Balengggek chickens quality and it. could reveal increased after it treated by 124 ConFed

Analysis of serological data to investigate heterogeneity of malaria transmission: a community-based cross-sectional study in an area conducting elimination in Indonesia.

BACKGROUND: Analysis of anti-malarial antibody responses has the potential to improve characterization of the variation in exposure to infection in low transmission settings, where conventional measures, such as entomological estimates and parasitaemia point prevalence become less sensitive and expensive to measure. This study evaluates the use of sero-epidemiological analysis to investigate heterogeneity of transmission in area conducting elimination in Indonesia. METHODS: Filter paper bloodspots and epidemiological data were collected through a community-based cross-sectional study conducted in two sub-districts in Sabang municipality, Aceh province, Indonesia in 2013. Antibody responses to merozoite surface protein 1 (MSP-119) and apical membrane antigen 1 (AMA-1) for Plasmodium falciparum and Plasmodium vivax were measured using indirect enzyme-linked immunosorbent assay (ELISA). Seroconversion rates (SCR) were estimated by fitting a simple reversible catalytic model to seroprevalence data for each antibody. Spatial analysis was performed using a Normal model (SaTScan v.9.4.2) to identify the clustering of higher values of household antibody responses. Multiple logistic regression was used to investigate factors associated with exposure. RESULTS: 1624 samples were collected from 605 households. Seroprevalence to any P. falciparum antigen was higher than to any P. vivax antigen, 6.9% (95% CI 5.8-8.2) vs 2.0% (95% CI 1.4-2.8). SCR estimates suggest that there was a significant change in P. falciparum transmission with no exposure seen in children under 5 years old. Plasmodium falciparum SCR in over 5 years old was 0.008 (95% CI 0.003-0.017) and 0.012 (95% CI 0.005-0.030) in Sukakarya and Sukajaya sub-districts, respectively. Clusters of exposure were detected for both P. falciparum and P. vivax, most of them in Sukajaya sub-district. Higher age, P. vivax seropositivity and use of long-lasting insecticide-treated bed net (LLIN) were associated with higher P. falciparum exposure. CONCLUSION: Analysis of community-based serological data helps describe the level of transmission, heterogeneity and factors associated with malaria transmission in Sabang. This approach could be an important additional tool for malaria monitoring and surveillance in low transmission settings in Indonesia

Mapping the High Risk Populations Against Coronavirus Disease 2019 in Padang West Sumatra Indonesia

Rapid outbreaks of coronavirus in 2019 (COVID-19), arising from acute coronavirus 2 (SARS-CoV-2) acute respiratory syndrome infections, have recently become a public health emergency. As one of the cities affected by COVID-19. The city of Padang found the highest case of COVID-19 in the province of West Sumatra and had a high risk of COVID-19 infection with a high rate of elderly population and comobidity diseases, namely diabetes, hypertension and tuberculosis. The purpose of this study is to mapping the distribution of high-risk populations to COVID-19 events in Padang City. This type of research is quantitative descriptive. Systematic data searches conducted for vulnerable groups to COVID-19 were obtained from the Padang City health profile database in 2019 and https://dinkes.padang.go.id/ to update the latest case of COVID-19. The research analysis unit was an administrative region according to the sub-district. The distribution of comorbidity was carried out using GIS analysis techniques using Arc-GIS 10.5 software. Padang City was recorded as the most widespread cluster of positive cases of COVID-19 in West Sumatra Province with a total of 99 confirmed positive cases, Padang Barat District with a total of 28 cases. The high risk population distribution data towards COVID-19 is the highest elderly in Kuranji District with a total of 9722, hypertension, diabetes mellitus, and tuberculosis highest in Koto Tangah District, with 11329, 4441 and 2583 cases. Conclusion The highest COVID-19 case in Padang city is not in the sub-district that has a high-risk population infected with COVID-19, but the sub-district must be monitored for those with high-risk population. The elderly population and comorbidities, hypertension and diabetes mellitus, tuberculosis are risk factors for COVID-19 infection. COVID-19 is a new disease that has become a pandemic. This disease must be wary of because of relatively rapid transmission, has a mortality rate that cannot be ignored