Genotype and allele frequencies for the five studied polymorphisms in SORCS1 gene in Alzheimer’s patients and controls stratified by ApoE carrier status.

<p>Abbreviations: MAF, minor allele frequency.</p><p>Genotypes and alleles are expressed as number (percentage). P values were calculated by χ² test 3×2 contingency table for genotype distribution and 2×2 contingency table for allele distribution.</p

Haplotype frequencies (>1%) of the five SNPs rs17277986, rs6584777, rs10884402, rs7078098 and rs950809 in SorCS1 gene and their relative risks for Alzheimer’s disease.

<p>Abbreviations: OR, odds ratio; 95% CI, 95% confidence interval; Psim, Simulated P values; NA, not available.</p>a<p>Alleles in total haplotype were arrayed in order of rs17277986, rs6584777, rs10884402, rs7078098 and rs950809.</p>b<p>Alleles in block 1 haplotype were arrayed in order of rs17277986 and rs6584777.</p>c<p>Alleles in block 2 haplotype were arrayed in order of rs10884402, rs7078098 and rs950809.</p>d<p>Adjusting for age and gender.</p

sj-pdf-1-jcb-10.1177_0271678X231153730 - Supplemental material for In vivo synaptic density loss correlates with impaired functional and related structural connectivity in Alzheimer’s disease

Supplemental material, sj-pdf-1-jcb-10.1177_0271678X231153730 for In vivo synaptic density loss correlates with impaired functional and related structural connectivity in Alzheimer’s disease by Junfang Zhang, Jie Wang, Xiaomeng Xu, Zhiwen You, Qi Huang, Yiyun Huang, Qihao Guo, Yihui Guan, Jun Zhao, Jun Liu, Wei Xu, Yulei Deng, Fang Xie and Binyin Li in Journal of Cerebral Blood Flow & Metabolism</p

Genotype and allele frequencies for rs17277986, rs6584777, rs12251340, rs10884402, rs7078098 and rs950809 SNPs and three genetic modes of inheritance for the five studied polymorphisms in SORCS1 gene.

<p>Abbreviations: OR, odds ratio; 95% CI, 95% confidence interval; MAF, minor allele frequency; NA, not available.</p><p>Genotypes and alleles are expressed as number (percentage). P values were calculated by χ² test 3×2 contingency table for genotype distribution and 2×2 contingency table for allele distribution.</p>a<p>Adjusting for age and gender.</p

Primer design.

<p>Primer design.</p

LD patterns of SNPs rs17277986,rs6585777, rs10884402, rs7078098 and rs950809.

<p>The linkage patterns between the 5 studied polymorphisms in all samples. The numbers in diamond represent the 100×D' in the form of standard color scheme. The upper bar denotes the relative distance among the studied polymorphisms. The bright red box denotes D' = 1 and LOD≥2; the pink box denotes D'<1 and LOD≥2.</p