2,366 research outputs found
Practice and the Comparative Study of Mysticism: \u3cem\u3eThe Yoga Sūtra\u3c/em\u3e and \u3cem\u3eThe Cloud of Unknowing\u3c/em\u3e
In his entry for the term “mysticism” in the updated edition of the Encyclopedia of Religion, Peter Moore writes that “the varieties of mystical practice tend to receive less scholarly attention than the varieties of experience or doctrine.”1 Bernard McGinn similarly claims that many studies of mysticism “so emphasize the moment of mystical contact . . . that they neglect the study of the fullness of the via mystica, particularly the ascetical and moral preparation for such contact.”2 Following from suggestions such as these, this article will do a comparative reading of two mystical texts: the Yoga Sūtra, a third-century Indian work attributed to Patañjali, and The Cloud of Unknowing, an anonymous fourteenth-century English treatise. Specifically, it will consider two dimensions of the mystical practices taught in these texts. These are the taking of vows and the contemplative stilling of the mind
Group Reputation and the Dynamics of Statistical Discrimination
Previous literature on statistical discrimination explained stereotypes based on the existence of multiple equilibria, in which principals have different self-confirming beliefs about different social groups (Arrow, 1973; Coate and Loury, 1993). However, the literature has not provided an account of where the principals' prior beliefs come from. Moreover, the static models dominating the literature do not offer relevant information about the dynamic paths that lead to each equilibrium. This paper develops a dynamic version of statistical discrimination in which economic players' forward-looking behaviors determine the dynamic paths to each equilibrium. Defining ``Group Reputation'' as the objective information shared by principals regarding the average characteristics of agents belonging to each group, this study identifies groups as advantaged or disadvantaged, based on their initial reputation states, and provides conditions by which a group can switch from one reputation state to another. By understanding this dynamic structure of reputation evolution, we examine the strategy that well-coordinated principals may voluntarily utilize to maximize their profits, helping the group in the reputation trap to improve its skill investment rate.Statistical Discrimination; Group Reputation; Reputation Trap; Forward-Looking Behavior
The Yersinia enterocolitica Ysa type III secretion system is expressed during infections both in vitro and in vivo.
Yersinia enterocolitica biovar 1B maintains two type III secretion systems (T3SS) that are involved in pathogenesis, the plasmid encoded Ysc T3SS and the chromosomally encoded Ysa T3SS. In vitro, the Ysa T3SS has been shown to be expressed only at 26°C in a high-nutrient medium containing an exceptionally high concentration of salt - an artificial condition that provides no clear insight on the nature of signal that Y. enterocolitica responds to in a host. However, previous research has indicated that the Ysa system plays a role in the colonization of gastrointestinal tissues of mice. In this study, a series of Ysa promoter fusions to green fluorescent protein gene (gfp) were created to analyze the expression of this T3SS during infection. Using reporter strains, infections were carried out in vitro using HeLa cells and in vivo using the mouse model of yersiniosis. Expression of green fluorescent protein (GFP) was measured from the promoters of yspP (encoding a secreted effector protein) and orf6 (encoding a structural component of the T3SS apparatus) in vitro and in vivo. During the infection of HeLa cells GFP intensity was measured by fluorescence microscopy, while during murine infections GFP expression in tissues was measured by flow cytometry. These approaches, combined with quantification of yspP mRNA transcripts by quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR), demonstrate that the Ysa system is expressed in vitro in a contact-dependent manner, and is expressed in vivo during infection of mice
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