Many Californians With Asthma Have Problems Understanding Their Doctor

Examines the prevalence and consequences of communication problems with doctors among adult asthma patients by education, income, insurance status, English proficiency, race/ethnicity, and nativity. Recommends customized education materials and programs

Dublin City University at CLEF 2007: Cross-Language Speech Retrieval Experiments

The Dublin City University participation in the CLEF 2007 CL-SR English task concentrated primarily on issues of topic translation. Our retrieval system used the BM25F model and pseudo relevance feedback. Topics were translated into English using the Yahoo! BabelFish free online service combined with domain-specific translation lexicons gathered automatically from Wikipedia. We explored alternative topic translation methods using these resources. Our results indicate that extending machine translation tools using automatically generated domainspecific translation lexicons can provide improved CLIR effectiveness for this task

Boron Nitride Nanosheets for Metal Protection

Although the high impermeability of graphene makes it an excellent barrier to inhibit metal oxidation and corrosion, graphene can form a galvanic cell with the underlying metal that promotes corrosion of the metal in the long term. Boron nitride (BN) nanosheets which have a similar impermeability could be a better choice as protective barrier, because they are more thermally and chemically stable than graphene and, more importantly, do not cause galvanic corrosion due to their electrical insulation. In this study, the performance of commercially available BN nanosheets grown by chemical vapor deposition as a protective coating on metal has been investigated. The heating of the copper foil covered with the BN nanosheet at 250 {\deg}C in air over 100 h results in dramatically less oxidation than the bare copper foil heated for 2 h under the same conditions. The electrochemical analyses reveal that the BN nanosheet coating can increase open circuit potential and possibly reduce oxidation of the underlying copper foil in sodium chloride solution. These results indicate that BN nanosheets are a good candidate for oxidation and corrosion protection, although conductive atomic force microscopy analyses show that the effectiveness of the protection relies on the quality of BN nanosheets.Comment: With Supporting Informatio

Multilingual search for cultural heritage archives via combining multiple translation resources

The linguistic features of material in Cultural Heritage (CH) archives may be in various languages requiring a facility for effective multilingual search. The specialised language often associated with CH content introduces problems for automatic translation to support search applications. The MultiMatch project is focused on enabling users to interact with CH content across different media types and languages. We present results from a MultiMatch study exploring various translation techniques for the CH domain. Our experiments examine translation techniques for the English language CLEF 2006 Cross-Language Speech Retrieval (CL-SR) task using Spanish, French and German queries. Results compare effectiveness of our query translation against a monolingual baseline and show improvement when combining a domain-specific translation lexicon with a standard machine translation system

Domain-specific query translation for multilingual access to digital libraries

Accurate high-coverage translation is a vital component of reliable cross language information access (CLIR) systems. This is particularly true of access to archives such as Digital Libraries which are often specific to certain domains. While general machine translation (MT) has been shown to be effective for CLIR tasks in information retrieval evaluation workshops, it is not well suited to specialized tasks where domain specific translations are required. We demonstrate that effective query translation in the domain of cultural heritage (CH) can be achieved by augmenting a standard MT system with domain-specific phrase dictionaries automatically mined from the online Wikipedia. Experiments using our hybrid translation system with sample query logs from users of CH websites demonstrate a large improvement in the accuracy of domain specific phrase detection and translation

Genetic basis of human circadian rhythm disorders.

Circadian rhythm disorders constitute a group of phenotypes that usually present as altered sleep-wake schedules. Until a human genetics approach was applied to investigate these traits, the genetic components regulating human circadian rhythm and sleep behaviors remained mysterious. Steady advances in the last decade have dramatically improved our understanding of the genes involved in circadian rhythmicity and sleep regulation. Finding these genes presents new opportunities to use a wide range of approaches, including in vitro molecular studies and in vivo animal modeling, to elevate our understanding of how sleep and circadian rhythms are regulated and maintained. Ultimately, this knowledge will reveal how circadian and sleep disruption contribute to various ailments and shed light on how best to maintain and recover good health

Variational ansatz-based quantum simulation of imaginary time evolution

Imaginary time evolution is a powerful tool for studying quantum systems. While it is possible to simulate with a classical computer, the time and memory requirements generally scale exponentially with the system size. Conversely, quantum computers can efficiently simulate quantum systems, but not non-unitary imaginary time evolution. We propose a variational algorithm for simulating imaginary time evolution on a hybrid quantum computer. We use this algorithm to find the ground-state energy of many-particle systems; specifically molecular hydrogen and lithium hydride, finding the ground state with high probability. Our method can also be applied to general optimisation problems and quantum machine learning. As our algorithm is hybrid, suitable for error mitigation and can exploit shallow quantum circuits, it can be implemented with current quantum computers.Comment: 14 page

Boron Nitride Nanosheets Improve Sensitivity and Reusability of Surface Enhanced Raman Spectroscopy

Surface enhanced Raman spectroscopy (SERS) is a useful multidisciplinary analytic technique. However, it is still a challenge to produce SERS substrates that are highly sensitive, reproducible, stable, reusable, and scalable. Here, we demonstrate that atomically thin boron nitride (BN) nanosheets have many unique and desirable properties to help solve this challenge. The synergic effect of the atomic thickness, high flexibility, stronger surface adsorption capability, electrical insulation, impermeability, high thermal and chemical stability of BN nanosheets can increase the Raman sensitivity by up to two orders, and in the meantime attain long-term stability and extraordinary reusability not achievable by other materials. These advances will greatly facilitate the wider use of SERS in many fields

HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs.

Maintenance of high-turnover tissues such as the epidermis requires a balance between stem cell proliferation and differentiation. The molecular mechanisms governing this process are an area of investigation. Here we show that HNRNPK, a multifunctional protein, is necessary to prevent premature differentiation and sustains the proliferative capacity of epidermal stem and progenitor cells. To prevent premature differentiation of progenitor cells, HNRNPK is necessary for DDX6 to bind a subset of mRNAs that code for transcription factors that promote differentiation. Upon binding, these mRNAs such as GRHL3, KLF4, and ZNF750 are degraded through the mRNA degradation pathway, which prevents premature differentiation. To sustain the proliferative capacity of the epidermis, HNRNPK is necessary for RNA Polymerase II binding to proliferation/self-renewal genes such as MYC, CYR61, FGFBP1, EGFR, and cyclins to promote their expression. Our study establishes a prominent role for HNRNPK in maintaining adult tissue self-renewal through both transcriptional and post-transcriptional mechanisms