Additional file 1: of Controllable Preparation of V2O5/Graphene Nanocomposites as Cathode Materials for Lithium-Ion Batteries

XRD patterns of vanadium precursors, CV curves, charge/discharge profiles of the V@GO-II composite. Discharge/charge voltage profiles of the V@GO-I composite. Raman peaks and their assignments of V2O5. Figure S1. XRD patterns of the nanosheet-assembled vanadium precursor/GO composite (blue line) and the nanoparticle-assembled vanadium precursor/GO composite (red line). Figure S2. CV curves of the V/GO-II composite at a scan rate of 0.1 mV s−1. Figure S3. Charge/discharge profiles of the V@GO-II composite at different densities. Figure S4. Discharge/charge voltage profiles of the V@GO-I composite (a) and the V@GO-I composite (b) at a current rate of 2C. (DOC 4760 kb

Additional file 1: Figure S1. of Improved Antitumor Efficacy and Pharmacokinetics of Bufalin via PEGylated Liposomes

The molecular formulas of the substances used in the formulation. (JPEG 103 kb

Additional file 3: Figure S2. of Improved Antitumor Efficacy and Pharmacokinetics of Bufalin via PEGylated Liposomes

Characteristic chromatogram of bufalin in plasma. (a) Blank plasma. (b) Blank plasma spiked with bufalin. (c) Blank plasma spiked with bufalin and resibufogenin (as internal standard). (d) Plasma samples spiked with resibufogenin 30 min after intravenous administration of bufalin entity. (e) Plasma samples spiked with resibufogenin 30 min after intravenous administration of bufalin-loaded liposomes. (f) Plasma samples spiked with resibufogenin 30 min after intravenous administration of bufalin-loaded PEGylated liposomes. (1) Bufalin; (2) Resibufogenin. (TIFF 1372 kb

Additional file 2: Table S1. of Improved Antitumor Efficacy and Pharmacokinetics of Bufalin via PEGylated Liposomes

Characterization of bufalin-loaded liposomes and bufalin-loaded PEGylated liposomes. Table S2. Inhibition of bufalin on six kinds of tumor cell lines. (DOCX 14 kb

Nitrogen-Doped Yolk–Shell-Structured CoSe/C Dodecahedra for High-Performance Sodium Ion Batteries

In this work, nitrogen-doped, yolk–shell-structured CoSe/C mesoporous dodecahedra are successfully prepared by using cobalt-based metal–organic frameworks (ZIF-67) as sacrificial templates. The CoSe nanoparticles are in situ produced by reacting the cobalt species in the metal–organic frameworks with selenium (Se) powder, and the organic species are simultaneously converted into nitrogen-doped carbon material in an inert atmosphere at temperatures between 700 and 900 °C for 4 h. For the composite synthesized at 800 °C, the carbon framework has a relatively higher extent of graphitization, with high nitrogen content (17.65%). Furthermore, the CoSe nanoparticles, with a size of around 15 nm, are coherently confined in the mesoporous carbon framework. When evaluated as novel anode materials for sodium ion batteries, the CoSe/C composites exhibit high capacity and superior rate capability. The composite electrode delivers the specific capacities of 597.2 and 361.9 mA h g^–1 at 0.2 and 16 A g^–1, respectively

Nanorod-Nanoflake Interconnected LiMnPO₄·Li₃V₂(PO₄)₃/C Composite for High-Rate and Long-Life Lithium-Ion Batteries

Olivine-type structured LiMnPO₄ has been extensively studied as a high-energy density cathode material for lithium-ion batteries. However, preparation of high-performance LiMnPO₄ is still a large obstacle due to its intrinsically sluggish electrochemical kinetics. Recently, making the composites from both active components has been proven to be a good proposal to improve the electrochemical properties of cathode materials. The composite materials can combine the advantages of each phase and improve the comprehensive properties. Herein, a LiMnPO₄·Li₃V₂(PO₄)₃/C composite with interconnected nanorods and nanoflakes has been synthesized via a one-pot, solid-state reaction in molten hydrocarbon, where the oleic acid functions as a surfactant. With a highly uniform hybrid architecture, conductive carbon coating, and mutual cross-doping, the LiMnPO₄·Li₃V₂(PO₄)₃/C composite manifests high capacity, good rate capability, and excellent cyclic stability in lithium-ion batteries. The composite electrodes deliver a high reversible capacity of 101.3 mAh g^–1 at the rate up to 16 C. After 4000 long-term cycles, the electrodes can still retain 79.39% and 72.74% of its maximum specific discharge capacities at the rates of 4C and 8C, respectively. The results demonstrate that the nanorod-nanoflake interconnected LiMnPO₄·Li₃V₂(PO₄)₃/C composite is a promising cathode material for high-performance lithium ion batteries

Dodecahedron-Shaped Porous Vanadium Oxide and Carbon Composite for High-Rate Lithium Ion Batteries

Carbon-based nanocomposites have been extensively studied in energy storage and conversion systems because of their superior electrochemical performance. However, the majority of metal oxides are grown on the surface of carbonaceous material. Herein, we report a different strategy of constructing V₂O₅ within the metal organic framework derived carbonaceous dodecahedrons. Vanadium precursor is absorbed into the porous dodecahedron-shaped carbon framework first and then <i>in situ</i> converted into V₂O₅ within the carbonaceous framework in the annealing process in air. As cathode materials for lithium ion batteries, the porous V₂O₅@C composites exhibit enhanced electrochemical performance, due to the synergistic effect of V₂O₅ and carbon composite

Carte de l'entrée de la rivière de Tréguier : levée sous les ordres de Mr. de Kearney Chevalier de St. louis Capitaine de frégate du Roy chargé par la Cour en 1768, 69 et 70 de la Reconnoissance des côtes du Royaume depuis Bayonne jusqu'a D'unkerque / par Mr. Loupia lieutenant d'infanterie et ingénieur Géographe de sa Majesté

Échelle(s) : Echelle de 1000 toises à six lignes pour 100 toises [= 13,5 cm], echelle d'une Lieu Marine à six lignes pour 100 toises [= 38,5 cm

DataSheet_1_Aboveground herbivory does not affect mycorrhiza-dependent nitrogen acquisition from soil but inhibits mycorrhizal network-mediated nitrogen interplant transfer in maize.pdf

Arbuscular mycorrhizal fungi (AMF) are considered biofertilizers for sustainable agriculture due to their ability to facilitate plant uptake of important mineral elements, such as nitrogen (N). However, plant mycorrhiza-dependent N uptake and interplant transfer may be highly context-dependent, and whether it is affected by aboveground herbivory remains largely unknown. Here, we used 15N labeling and tracking to examine the effect of aboveground insect herbivory by Spodoptera frugiperda on mycorrhiza-dependent N uptake in maize (Zea mays L.). To minimize consumption differences and 15N loss due to insect chewing, insect herbivory was simulated by mechanical wounding and oral secretion of S. frugiperda larvae. Inoculation with Rhizophagus irregularis (Rir) significantly improved maize growth, and N/P uptake. The 15N labeling experiment showed that maize plants absorbed N from soils via the extraradical mycelium of mycorrhizal fungi and from neighboring plants transferred by common mycorrhizal networks (CMNs). Simulated aboveground leaf herbivory did not affect mycorrhiza-mediated N acquisition from soil. However, CMN-mediated N transfer from neighboring plants was blocked by leaf simulated herbivory. Our findings suggest that aboveground herbivory inhibits CMN-mediated N transfer between plants but does not affect N acquisition from soil solutions via extraradical mycorrhizal mycelium.</p

Synthesis and Biological Evaluation of Novel σ₁ Receptor Ligands for Treating Neuropathic Pain: 6‑Hydroxypyridazinones

By use of the 6-hydroxypyridazinone framework, a new series of potent σ₁ receptor ligands associated with pharmacological antineuropathic pain activity was synthesized and is described in this article. In vitro receptor binding studies revealed high σ₁ receptor affinity (<i>K</i>_i σ₁ = 1.4 nM) and excellent selectivity over not only σ₂ receptor (1366-fold) but also other CNS targets (adrenergic, μ-opioid, sertonerigic receptors, etc.) for 2-(3,4-dichlorophenyl)-6-(3-(piperidin-1-yl)­propoxy)­pyridazin-3­(2<i>H</i>)-one (compound <b>54</b>). Compound <b>54</b> exhibited dose-dependent antiallodynic properties in mouse formalin model and rats chronic constriction injury (CCI) model of neuropathic pain. In addition, functional activity of compound <b>54</b> was evaluated using phenytoin and indicated that the compound was a σ₁ receptor antagonist. Moreover, no motor impairments were found in rotarod tests at antiallodynic doses and no sedative side effect was evident in locomotor activity tests. Last but not least, good safety and favorable pharmacokinetic properties were also noted. These profiles suggest that compound <b>54</b> may be a member of a novel class of candidate drugs for treatment of neuropathic pain