25,463 research outputs found
Sign Changes of Intrinsic Spin Hall Effect in Semiconductors and Simple Metals: First-Principles Calculations
First-principles calculations are applied to study spin Hall effect in
semiconductors and simple metals. We found that intrinsic spin Hall
conductivity (ISHC) in realistic materials shows rich sign changes, which may
be used to distinguish the effect from the extrinsic one. The calculated ISHC
in n-doped GaAs can be well compared with experiment, and it differs from the
sign obtained from the extrinsic effect. On the other hand, the ISHC in W and
Au, which shows opposite sign respectively, is robust and not sensitive to the
disorder.Comment: 4 pages, 4 figure
Studies of the role of nf-κb in controlling osteoclast differentiation and bone loss
Increased osteoclast (OC) bone resorption and/or decreased osteoblast (OB) bone formation contribute to bone loss in osteoporosis and rheumatoid arthritis (RA). Findings of the basic and translational research presented in this thesis demonstrate a number of mechanisms by which cytokine-induced NF-κB activation controls bone resorption and formation: 1) Tumour necrosis factor-α (TNF) expands pool of OC precursors (OCPs) by promoting their proliferation through stimulation of the expression of macrophage colony stimulating factor (M-CSF) receptor, c-Fms, and switching M-CSF-induced resident (M2) to inflammatory (M1) macrophages with enhanced OC forming potential and increased production of inflammatory factors through induction of NF-κB RelB; 2) Similar to RANKL, TNF sequentially activates transcriptional factors NF-κB p50 and p52 followed by c-Fos and then NFATc1 to induce OC differentiation. However, TNF alone nduces very limited OC differentiation. In contrast, it pre-activates OCPs to express cFos which cooperates with interleukin-1 (IL-1) produced by these OCPs in an autocrine mechanism by interacting with bone matrix to mediate the OC terminal differentiation and bone resorption from these pre-activated OCPs. 3) TNF-induced OC formation is independent of RANKL but it also induces NF-κB2 p100 to limit OC formation and bone
resorption, and thus p100 deletion accelerates joint destruction and systemic bone loss in TNF-induced RA; 4) TNF receptor associated factor-3 (TRAF3) limits OC
differentiation by negatively regulating non-canonical NF-κB activation and RANKL induces TRAF3 ubiquitination and lysosomal degradation to promote OC differentiation.
Importantly, a lysosomal inhibitor that inhibits TRAF3 degradation prevents ovariectomy-induced bone loss; 5) RelB and Notch NICD bind RUNX2 to inhibit OB differentiation and RelB:p52 dimer association with NICD inhibit OB differentiation by enhancing the binding of RBPjκ to Hes1. These findings suggest that non-canonical NF- κB signaling could be targets to develop new therapies for RA or osteoporosis. For example 1) Agents that degrade TNF-induced RelB could block M1 macrophage differentiation to inhibit inflammation and joint destruction for the therapy of RA; 2)Agents that prevent p100 processing or TRAF3 degradation could inhibit bone resorption and also stimulate bone formation simultaneously for the therapy of osteoporosis
Study on QoS support in 802.11e-based multi-hop vehicular wireless ad hoc networks
Multimedia communications over vehicular ad hoc networks (VANET) will play an important role in the future intelligent transport system (ITS). QoS support for VANET therefore becomes an essential problem. In this paper, we first study the QoS performance in multi-hop VANET by using the standard IEEE 802.11e EDCA MAC and our proposed triple-constraint QoS routing protocol, Delay-Reliability-Hop (DeReHQ). In particular, we evaluate the DeReHQ protocol together with EDCA in highway and urban areas. Simulation results show that end-to-end delay performance can sometimes be achieved when both 802.11e EDCA and DeReHQ extended AODV are used. However, further studies on cross-layer optimization for QoS support in multi-hop environment are required
Does a proton "bubble" structure exist in the low-lying states of 34Si?
The possible existence of a "bubble" structure in the proton density of
Si has recently attracted a lot of research interest. To examine the
existence of the "bubble" structure in low-lying states, we establish a
relativistic version of configuration mixing of both particle number and
angular momentum projected quadrupole deformed mean-field states and apply this
state-of-the-art beyond relativistic mean-field method to study the density
distribution of the low-lying states in Si. An excellent agreement with
the data of low-spin spectrum and electric multipole transition strengths is
achieved without introducing any parameters. We find that the central
depression in the proton density is quenched by dynamic quadrupole shape
fluctuation, but not as significantly as what has been found in a beyond
non-relativistic mean-field study. Our results suggest that the existence of
proton "bubble" structure in the low-lying excited and states
is very unlikely.Comment: 6 pages, 8 figures and 1 table, accepted for publication in Physics
Letters
Associated production of the charged Higgs boson and single top quark at the LHC
The left-right twin Higgs(LRTH) model predicts the existence of the charged
Higgs . In this paper, we study the production of the charged Higgs
boson with single top quark via the process at the
Large Hadron Collider(LHC). The numerical results show that the
production cross section can reach the level of in the reasonable
parameter space of the LRTH model. We expect that, as long as it is not too
heavy, the possible signatures of the heavy charged Higgs boson
might be detected via the decay mode at the LHC
experiments.Comment: This paper has been withdrawn by the author(s) due to some mistakes
in this pape
Neutrino emission from a GRB afterglow shock during an inner supernova shock breakout
The observations of a nearby low-luminosity gamma-ray burst (GRB) 060218
associated with supernova SN 2006aj may imply an interesting astronomical
picture where a supernova shock breakout locates behind a relativistic GRB jet.
Based on this picture, we study neutrino emission for early afterglows of GRB
060218-like GRBs, where neutrinos are expected to be produced from photopion
interactions in a GRB blast wave that propagates into a dense wind.
Relativistic protons for the interactions are accelerated by an external shock,
while target photons are basically provided by the incoming thermal emission
from the shock breakout and its inverse-Compton scattered component. Because of
a high estimated event rate of low-luminosity GRBs, we would have more
opportunities to detect afterglow neutrinos from a single nearby GRB event of
this type by IceCube. Such a possible detection could provide evidence for the
picture described above.Comment: 6 pages, 2 figures, accepted for publication in MNRA
Orbital-transverse density-wave instabilities in iron-based superconductors
Besides the conventional spin-density-wave (SDW) state, a new kind of
orbital-transverse density-wave (OTDW) state is shown to exist generally in
multi-orbital systems. We demonstrate that the orbital character of Fermi
surface nesting plays an important role in density responses. The relationship
between antiferromagnetism and structural phase transition in LaFeAsO (1111)
and BaFeAs (122) compounds of iron-based superconductors may be
understood in terms of the interplay between the SDW and OTDW with a
five-orbital Hamiltonian. We propose that the essential difference between 1111
and 122 compounds is crucially determined by the presence of the
two-dimensional -like Fermi surface around (0,0) being only in 1111
parent compounds.Comment: several parts were rewritten for clarity. 6 pages, 3 figures, 1 tabl
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