Chinese Foreign Policy in Changing Perspective--A Case Study of the Three World Doctrine

China has in recent years embarked on a fresh policy of close cooperation with her former antagonists, the Western countries, not only in economic areas, but also on social, military and political issues. Does this mean that China has given up her highly publicized third world position? Or did China ever genuinely belong with the third world in the past? These questions are explored in the thesis through careful analyses of the origins of China\u27s foreign policies as well as comparative observations of their applications to different countries at different stages. Rather than isolating individual variables, as some writers do, in measuring their impact on the outcome of China\u27s policy, this study takes a contextual approach, combining normative analysis with empirical observation, and blending historical and contemporary perspectives. It concludes that China\u27s differentiation of international political forces should not suggest that China was identifying herself permanently with any one of them, but rather was simply adopting a dialectical approach toward world politics

CKM and PMNS mixing matrix from SO(2)SO(2) flavor symmetry

The relation between quark masses and CKM mixing is studied based on an approximate chiral $SO(2)_L\times SO(2)_R$ flavor symmetry of quark mass matrix. In mass hierarchy limit, the mass ratio effect to CKM mixing is suppressed, which separates mass hierarchy and quark flavor mixing into two independent problems. We show that CKM mixing is dominated by two left-handed $SO(2)_L^{u,d}$ symmetry while mass hierarchy only provides slight corrections. The same mixing structure is generalized to lepton sector with extended Dirac neutrinos. The common flavor mixing provides a novel comprehension on the relation between quark CKM mixing and lepton PMNS mixing.Comment: 6 papers 1 figur

ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?

Among the three human apolipoprotein E (apoE) isoforms, apoE4 increases the risk of Alzheimer’s disease (AD). While transporting cholesterol is a primary function, apoE also regulates amyloid-β (Aβ) metabolism, aggregation, and deposition. Although earlier work suggests that different affinities of apoE isoforms to Aβ might account for their effects on Aβ clearance, recent studies indicate that apoE also competes with Aβ for cellular uptake through apoE receptors. Thus, several factors probably determine the variable effects apoE has on Aβ. In this Review, we examine biochemical, structural, and functional studies and propose testable models that address the complex mechanisms underlying apoE-Aβ interaction and how apoE4 may increase AD risk and also serve as a target pathway for therapy

Zoom in on neurodegeneration

Despite the existence of several scientific journals that publish research papers and reviews related to neurodegenerative diseases, a journal specifically devoted to the molecular and cellular aspects of disease mechanisms is lacking. Molecular Neurodegeneration is an open-access, peer-reviewed, online journal created to publish original research articles that address i) the mechanisms of neurodegeneration at the cellular, subcellular and molecular levels and ii) potential therapeutic interventions for neurodegenerative diseases. Through publication of reviews, editorial commentaries, and meeting reports, Molecular Neurodegeneration will also provide a forum to enhance the exchange of ideas and promote debate that is essential for scientific progress. Molecular Neurodegeneration will enable scientists to rapidly communicate their important research discoveries to their colleagues around the world

Safety estimation for a new model of regenerative and frictional cutting dynamics

Acknowledgements This research is supported by National Natural Science Foundation of China (Grants No. 11872147, 12072068, 11932015 and 11502048).Peer reviewedPostprin