Research on security risks and countermeasures of IPv6 network in the new era

In recent years, with the development of new infrastructure, especially the needs of 5G, Internet of Things, cloud services, data centers and other incremental large-scale construction, these “new increments” can be completely based on IPv6, or even pure IPv6 deployment to improve quality, reduce costs, and increase effi ciency. Therefore, in the process of constructing IPv6 network, how to ensure the overall security and stability of the network, and do a good job of network security protection and risk response to the maximum is very important. Based on this, this paper studies the security risk points of IPv6 network protocol and puts forward several security countermeasures for reference

Analysis of the Gravitational Wave Background Using Gamma-Ray Pulsar Timing Arrays with Next-Generation Detectors

In this work, we investigate the potential of gamma-ray pulsar time array (PTA) on gravitational waves background (GWB) using future gamma-ray detectors with larger effective areas. We consider both spaceborne detectors and ground-based imaging air Cherenkov telescope arrays (IACTs). We simulated the detected photons from pulsars using the response of hypothetical detectors taking into account the backgrounds and analyzed the sensitivities. Our results showed that thanks to the higher statistics of IACTs, the PTA using IACTs can improve significantly the performance compared with the PTA using Fermi-LAT data.Comment: 6 pages, 5 figures, Accepted for publication in PR

Anesthetic Isoflurane Increases Phosphorylated Tau Levels Mediated by Caspase Activation and Aβ Generation

Anesthetic isoflurane has been shown to promote Alzheimer’s disease (AD) neuropathogenesis by inducing caspase activation and accumulation of β-amyloid (Aβ). Phosphorylation of tau protein is another important feature of AD neuropathogenesis. However, the effects of isoflurane on phosphorylated tau levels remain largely to be determined. We therefore set out to determine whether isoflurane can increase phosphorylated tau levels. 5 to 8 month-old wild-type and AD transgenic mice [B6.Cg-Tg (APPswe, PSEN1dE9)85Dbo/J] were treated with 1.4% isoflurane for two hours. The mice brain tissues were harvested at six, 12 and 24 hours after the anesthesia. For the in vitro studies, primary neurons from wild-type and the AD transgenic mice were exposed to 2% isoflurane for six hours, and were harvested at the end of anesthesia. The harvested brain tissues and neurons were subjected to Western blot analysis by which the levels of phosphorylated tau protein at Serine 262 (Tau-PS262) were determined. Here we show that the isoflurane anesthesia increased Tau-PS262 levels in brain tissues and primary neurons from the wild-type and AD transgenic mice. Moreover, the isoflurane anesthesia may induce a greater increase in Tau-PS262 levels in primary neurons and brain tissues from the AD transgenic mice. Finally, caspase activation inhibitor Z-VAD and Aβ generation inhibitor L-685,458 attenuated the isoflurane-induced increases in Tau-PS262 levels. In conclusion, clinically relevant isoflurane anesthesia increases phosphorylated tau levels, which may result from the isoflurane-induced caspase activation and Aβ generation. These findings will promote more studies to determine the effects of anesthetics on tau phosphorylation

Ultraviolet photoluminescence from 3C-SiC nanorods

An intensive sharp photoluminescence at 3.3 eV is observed from single-crystal 3C-SiC nanorods. Structural characterization reveals that the nanorods contain a fairly large amount of threefold stacking faults. We tentatively attribute the emission to these stalking faults, which structurally resemble 6H-SiC nano-layers of 1.5 nm embedded in a 3C-SiC matrix. The emission mechanism is discussed in terms of spontaneous polarization at the stacking faults