沃度保兒謨ニ因セル濕疹

Evaluation of CNA-IC50 correlations by known cancer driver mutations. Distributions of PCCs for cancer cell lines with mutated or wild-type proto-oncogenes or tumor suppressors as depicted in each figure. The rank position of negatively correlated drugs (p < 0.10) is shown. (EPS 975 kb

sj-docx-1-hol-10.1177_09596836231197736 – Supplemental material for Wells, fields and the emergence of early-to-middle Holocene villages in the Huai River region, China: Contesting regional similarities and differences on prehistoric water management with new archaeological and palaeo-environmental evidence

Supplemental material, sj-docx-1-hol-10.1177_09596836231197736 for Wells, fields and the emergence of early-to-middle Holocene villages in the Huai River region, China: Contesting regional similarities and differences on prehistoric water management with new archaeological and palaeo-environmental evidence by Yijie Zhuang, Xingtao Wei, Lina Zhuang, Xiaohu Zhang and Junjie Xu in The Holocene</p

Highly Asymmetric Phthalocyanine as a Sensitizer of Graphitic Carbon Nitride for Extremely Efficient Photocatalytic H₂ Production under Near-Infrared Light

Highly asymmetric zinc phthalocyanine derivative (Zn-<i>tri</i>-PcNc) with intense near-IR light (650–800 nm) absorption is utilized as a sensitizer to extend the spectral response region of graphitic carbon nitride (g-C₃N₄) from ∼450 nm to more than 800 nm. Ultraviolet–visible light (UV-vis) diffuse reflectance absorption spectra (DRS), photoluminescence (PL) spectra, time-resolved photoluminescence spectra (TRPS), and energy band structure analyses are adopted to investigate the photogenerated electron transfer process between Zn-<i>tri</i>-PcNc and g-C₃N₄ on both thermodynamics and dynamics aspects. After optimizing the photocatalytic condition and adding chenodeoxycholic acid (CDCA) as coadsorbent, Zn-<i>tri</i>-PcNc sensitized g-C₃N₄ photocatalyst shows a H₂ production efficiency of 125.2 μmol h^–1 under visible/near-IR-light (λ ≥ 500 nm) irradiation, corresponding to a turnover number (TON) of 5008 h^–1 with an extremely high apparent quantum yield (AQY) of 1.85% at 700 nm monochromatic light irradiation. The present work should be the rarely fundamental investigation on the utilization of near-IR light of solar radiation for the photocatalytic H₂ production from water splitting over a dye-sensitized semiconductor

Indirect Detection of Glycosidases Using Amperometry

Glycosidases are essential enzymes that cleave glycoside bonds. The presence of glycosidases have been widely used to detect pathogens, label cells/tissues, and report specific diseases. We have developed a rapid electrochemical assay to detect glycosidases. Exposure of electrochemically inactive substrates to glycosidases releases glucose, which can be measured easily using an electrochemical cell. Five different glycosidases were detected rapidly within 1 h using disposable electrodes. This assay could readily be incorporated into repurposed glucose meters to rapidly detect glycosidases, which in turn could be useful to report the presence of a pathogen or illness

¹⁴C dates of the Quanhu and Anban archaeological sites in the Guanzhong Basin (modified from Zhang et al., 2010 [39]).

<p>The series of GZ-dates are AMS ¹⁴C dates obtained by the Guangzhou Institute of Geochemistry, CAS and State Key Laboratory of Nuclear Physics and Technology of Peking University. The No-GZ series are conventional ¹⁴C dates obtained by the Laboratory of Nuclide and ¹⁴C Chronology of Institute of Geology and Geophysics, CAS. A–ash; S–ancient soil with rich charcoal; C–charcoal.</p

Some shell tools and ornaments from the Quanhu and Baijiacun archaeological sites in Guanzhong Basin (modified after the Institute of Archaeology Chinese Academy of Social Sciences, 1994 [56] and The Archaeology Department of Peking University and the Institute of Archaeology Chinese Academy of Social Sciences, 2003 [<b>58</b>]).

<p>A,D, shell knife; B,C,E,F, shell reaphook; G, shell arrowhead; H, shell pendant; I, shell loop (part).</p

Variations in mollusk shell tool (red curve) and ornament (blue curve) quantities in Guanzhong Basin during mid-Neolithic.

<p>The archaeological sites labeled on the X axis are listed according to their longitudes with the westernmost GTY on the left and the easternmost Quanhu on the right. GTY–Guantaoyuan; BSL–Beishouling; AB–Anban; HXZ–Huxizhuang; BJC–Baijiacun; JZ–Jiangzhai; QH–Quanhu.</p

Archaeostratigraphy of the Quanhu (QH2) archaeological site and field photo of the QH-H3 archaeological site.

<p>A. Archaeostratigraphy of the QH2 archaeological site, showing from the left to the right stratigraphy photo, archaeostratigraphy with indication of mollusk (solid circles) and age (solid rectangle) sampling layers, description of the archaeostratigraphy of the QH2 site. B. Field photo of the QH-H3 archaeological site with mollusk (solid circles) and age (solid rectangle) sampling layers indicated.</p

Gastropod and bivalve mollusks found in the Quanhu (QH2 and QH-H3) and Anban (AB-AH2) archaeological sites.

<p>A,B, <i>Cipangopaludina chinensis</i>, QH2 0.9–0.8 m; C, D, <i>Cipangopaludina chinensis</i>, QH2 0.9–0.8 m; E,F, <i>Cipangopaludina chinensis</i>, QH2 1.0–0.9 m; G,H, <i>Cipangopaludina chinensis</i>, QH2 1.0–0.9 m; I,J, <i>Cipangopaludina chinensis</i>, QH-H3; K,L, <i>Cipangopaludina chinensis</i>, QH-H3; M,N, <i>Cipangopaludina chinensis</i>, QH2 1.6–1.5 m; O,P, <i>Unio douglasiae</i>, AB-AH2. Scale bars = 10 mm.</p

Covalently Cross-Linked Chemistry of a Three-Dimensional Network Binder at Limited Dosage Enables Practical Si/C Composite Electrode Applications

Currently, Si (or SiOx, 1 x < 2) and graphite composite (Si/C) electrodes (e.g., Si/C450 and Si/C600 with specific capacities of 450 and 600 mAh g–1 at 0.1 C, respectively) have become the most promising alternative to traditional graphite anodes toward high-energy lithium-ion battery (LIB) applications by virtue of their higher specific capacity compared to graphite ones and improved cycle performance compared to Si (or SiOx) ones. However, such composite electrodes remain challenging to practical for implementation owing to electrode structure disintegration and interfacial instability caused by a large volume change of inner Si-based particles. Herein, we develop a covalent-bond cross-linking network binder for Si/C450 and Si/C600 electrodes via reversible addition–fragmentation chain transfer (RAFT) polymerization. The as-developed binder with a 3 mol % cross-linker of other monomers [termed P(SH-BA3%)] achieves improved mechanical and adhesive properties and decreased Si/C anode volume expansion, compared to the linear binder counterpart. Impressively, the P(SH-BA3%) binder at only 3 wt % dosage enables 83.56% capacity retention after 600 cycles at 0.5 C in Si/C450 anode based half-cells and retains 86.42% capacity retention at 0.3 C after 200 cycles and 80.95% capacity retention at 0.5 C after 300 cycles in LiNi0.8Co0.1Mn0.1O2 cathode (15 mg cm–2) based homemade soft package full cells. This work provides insight into binder cross-linking chemistry under limited dosage and enlightens cross-linking binder design toward practical Si/C electrode applications